Wilms' tumour: connecting tumorigenesis and organ development in the kidney. - Wikidata - awgldk - TriplyDB

Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

http://www.wikidata.org/entity/Q36234726

about

Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor Contribution of multiparameter flow cytometry immunophenotyping to the diagnostic screening and classification of pediatric cancer A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation STAT1 activation regulates proliferation and differentiation of renal progenitors The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/Omi Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors Wilms' tumor: biology, diagnosis and treatment Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and Treatment Nonviral oncogenic antigens and the inflammatory signals driving early cancer development as targets for cancer immunoprevention WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation Lin28 sustains early renal progenitors and induces Wilms tumor The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification von Hippel-Lindau disease-associated hemangioblastomas are derived from embryologic multipotent cells Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis Association between TP53 gene Arg72Pro polymorphism and Wilms' tumor risk in a Chinese population.Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.Evolutionary conservation of zinc finger transcription factor binding sites in promoters of genes co-expressed with WT1 in prostate cancer Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs Expression of stem cell markers in the human fetal kidney A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk.Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours.WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny.Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms' tumor onset Discovering tumor suppressor genes through genome-wide copy number analysis.Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours WT1: a weak spot in KRAS-induced transformation Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.Deletions of 16q in Wilms tumors localize to blastemal-anaplastic cells and are associated with reduced expression of the IRXB renal tubulogenesis gene cluster.miRNA profiles as a predictor of chemoresponsiveness in Wilms' tumor blastema.Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1 WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line Signaling pathways in renal cell carcinoma.Clear cell sarcoma of the kidney demonstrates an embryonic signature indicative of a primitive nephrogenic origin A high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation Inactivation of X-linked tumor suppressor genes in human cancer.WT1/EGR1-mediated control of STIM1 expression and function in cancer cells

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Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

http://www.wikidata.org/entity/Q36234726

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Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

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Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

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Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

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Nature Reviews Cancer

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Wilms' tumour: connecting tumorigenesis and organ development in the kidney.

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Daniel A Haber

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Miguel N Rivera

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P2860

Parental imprinting of the mouse H19 gene

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1

Defects in enteric innervation and kidney development in mice lacking GDNF

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15

Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects

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