Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.
about
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing populationMolecular biology of lung cancer: clinical implicationsWilms tumor 1 mutations in the pathogenesis of acute myeloid leukemiaEpigenetic regulators and their impact on therapy in acute myeloid leukemiaTargeting NADPH oxidases for the treatment of cancer and inflammationSynthetic lethality in lung cancer and translation to clinical therapiesDrugging the addict: non-oncogene addiction as a target for cancer therapyDNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemiaRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cellsUse of RNAi screens to uncover resistance mechanisms in cancer cells and identify synthetic lethal interactions.A primer on using pooled shRNA libraries for functional genomic screensWT1 interacts with MAD2 and regulates mitotic checkpoint functionWT1: a weak spot in KRAS-induced transformationHigh-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions.Development of synthetic lethality anticancer therapeutics.Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1WT1 promotes cell proliferation in non-small cell lung cancer cell lines through up-regulating cyclin D1 and p-pRb in vitro and in vivo.Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene.RAS transformation requires CUX1-dependent repair of oxidative DNA damage.Wilms' tumor 1 (WT1) expression and prognosis in solid cancer patients: a systematic review and meta-analysis.Drugging the undruggable RAS: Mission possible?RAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally.Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer.Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma.'Big data' approaches for novel anti-cancer drug discovery.RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.Impact of mutational status on survival in low-grade serous carcinoma of the ovary or peritoneum.A novel immunogenic CS1-specific peptide inducing antigen-specific cytotoxic T lymphocytes targeting multiple myeloma.Senescence Process in Primary Wilms' Tumor Cell Culture Induced by p53 Independent p21 ExpressionProtein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.A RAS renaissance: emerging targeted therapies for KRAS-mutated non-small cell lung cancer.Tumour-associated antigens: considerations for their use in tumour immunotherapy.Never-ageing cellular senescenceTowards systematic functional characterization of cancer genomes.WT1 in disease: shifting the epithelial-mesenchymal balance.RAS signalling in the colorectum in health and disease.Mouse models for lung cancer
P2860
Q21563374-642C8C57-AD0A-4158-BF6D-5FDC49DBF187Q24610335-6ABBC0C2-7A16-48D8-B517-1FBABC88C027Q26744111-3E30F3D7-9C70-4278-AF6F-79C1CDCAF553Q26765402-C27D580F-0EEA-42C8-9579-3359214932E5Q26851163-7F7DCA53-5FBA-4B88-A201-F9F402704D58Q28072904-9D592926-5EF0-4922-A729-69641848A538Q28079559-3010370F-4CF2-45E6-BF26-01887B6E2059Q28253465-B85635EA-D4D8-4171-9F3D-12C6C484636CQ28260541-5931B466-18EB-483D-B14D-4BE585724FD9Q30531111-B9B13059-E025-4404-BC1A-8DE12D097EE6Q33651791-5B1996E8-3A27-439E-BEF7-F5CCDCCA760FQ34137070-DFC8E2FA-F2AB-4200-88AF-286D5D52BFF9Q34221445-A7FC8C2D-221E-4B44-BCAE-83BB41E46891Q34245506-2ECA854B-F811-4364-8244-4E234B4C59DAQ34247032-F5F3BF3E-FE87-40C3-9978-FC57F94E0526Q34380368-3F1E8959-EE58-4DA5-A75C-6DD6BB9229C7Q34617481-2A2D0C68-CF58-4400-BC74-33457806E586Q34924201-7F9E69A5-0908-46A2-9A35-740A43D16F19Q35095712-CFE1C0AA-D6FD-4C70-B808-49162A611734Q35117739-25141544-7503-4E61-9B36-933169D92C70Q35157134-D0BFA0D2-12CD-45DB-8E66-6EC0F5816216Q35163434-F264A3D2-59D0-4607-9CC1-C5D063D79259Q35683647-5B9D6027-F866-4E3B-8E9A-3499C50C068EQ35894216-77D65681-A2F5-423F-8932-53A77E7C729AQ36268425-014E827D-60AE-4FCB-B8B8-21F41BE41EA7Q36331953-BC44AA5C-4A28-4264-9E01-194C36BE9713Q36360310-4ECEBBA8-AD1B-4505-906D-A40D2DF402BEQ36398735-EB6B5DEF-E27F-4A36-A04C-54022D9E1743Q36750622-71206823-6FFB-45C6-B2B8-A9B9487EF384Q37284373-839557F1-1ACD-481C-90DF-75F1773547BBQ37290498-3010154A-137D-47B8-A69D-B6EB0265F111Q37491175-DE06BFB5-DF83-43B4-A8B1-5008C9EF0407Q37632641-C73A96EE-2669-47AB-A0FE-7A411A365FBBQ37724940-9A2EA472-BEFA-46CA-B3B1-03E7D51E9EE9Q37848203-9861903F-0118-4C33-8BB6-5C2A9F9BD8B8Q37874368-43EAFCEA-9A9C-4C2D-AA16-C15F66DD4669Q37890867-E249B20D-B89F-44B4-AFF0-EB031AC1AAECQ37940867-CF4AC9C1-855A-45CA-8EE5-F64889346C20Q37974687-F1045F5D-6338-44B8-87F7-5EF8D3E9784EQ38088500-B98CB7E5-A362-477B-95D1-CC0822557B2B
P2860
Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Wilms tumor 1 (WT1) regulates ...... nce in mouse and human models.
@ast
Wilms tumor 1 (WT1) regulates ...... nce in mouse and human models.
@en
Wilms tumor 1
@nl
type
label
Wilms tumor 1 (WT1) regulates ...... nce in mouse and human models.
@ast
Wilms tumor 1 (WT1) regulates ...... nce in mouse and human models.
@en
Wilms tumor 1
@nl
prefLabel
Wilms tumor 1 (WT1) regulates ...... nce in mouse and human models.
@ast
Wilms tumor 1 (WT1) regulates ...... nce in mouse and human models.
@en
Wilms tumor 1
@nl
P2093
P2860
P356
P1476
Wilms tumor 1 (WT1) regulates ...... ence in mouse and human models
@en
P2093
Anna K Gillespie
Aravind Subramanian
Chenwei Lin
David E Root
E Alejandro Sweet-Cordero
Gregory Hinkle
Leanne C Sayles
Randal G Walker
Sakina Saif
P2860
P304
P356
10.1172/JCI44165
P407
P577
2010-10-25T00:00:00Z