Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cellsConcerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motilityTargeting migration inducting gene-7 inhibits carcinoma cell invasion, early primary tumor growth, and stimulates monocyte oncolytic activitySrc-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migrationRegulation of cell motility by mitogen-activated protein kinaseEnhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent proteinOverexpression of carcinoma and embryonic cytotrophoblast cell-specific Mig-7 induces invasion and vessel-like structure formationαV integrins in angiogenesis and cancerp66Shc as a switch in bringing about contrasting responses in cell growth: implications on cell proliferation and apoptosisUrokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivoIntegrins in cancer: biological implications and therapeutic opportunitiesVinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities.Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner.Phosphorylation of p130Cas initiates Rac activation and membrane ruffling.Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility.Injury and EGF mediate the expression of alpha6beta4 integrin subunits in corneal epithelium.Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGFp66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis.Small molecule alpha(v) integrin antagonists: novel anticancer agents.Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration.The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry.EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1.Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectinInduction of carcinoma cell migration on vitronectin by NF-kappa B-dependent gene expression.Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model.SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.Treatment of marrow stroma with interferon-alpha restores normal beta 1 integrin-dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors. Role of MIP-1 alpha.Vitronectin expression in differentiating neuroblastic tumors: integrin alpha v beta 5 mediates vitronectin-dependent adhesion of retinoic-acid-differentiated neuroblastoma cellsStimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.Thrombospondin modulates alpha v beta 3 function through integrin-associated proteinCross talk between adhesion molecules: control of N-cadherin activity by intracellular signals elicited by beta1 and beta3 integrins in migrating neural crest cells.Bifurcation of cell migratory and proliferative signaling by the adaptor protein Shc.Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage.Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins.Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell ActivationScaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.
P2860
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P2860
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@ast
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@en
type
label
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@ast
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@en
prefLabel
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@ast
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@en
P2093
P2860
P356
P1476
Receptor tyrosine kinase signa ...... t not adhesion on vitronectin.
@en
P2093
P2860
P304
P356
10.1083/JCB.127.3.859
P407
P577
1994-11-01T00:00:00Z