Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins.
about
Receptor complexes for each of the Class 3 SemaphorinsCis and trans interactions of L1 with neuropilin-1 control axonal responses to semaphorin 3A.Cancer cells cut homophilic cell adhesion molecules and runNr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesisThe Wnt Target Gene L1 in Colon Cancer Invasion and MetastasisCell Adhesion Molecules and Ubiquitination-Functions and SignificanceActivity dependent CAM cleavage and neurotransmissionL1cam is crucial for cell locomotion and terminal translocation of the Soma in radial migration during murine corticogenesisA Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous SystemsAutolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activityEctodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell deathDeficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularitySialoglycoproteins and N-glycans from secreted exosomes of ovarian carcinoma cellsFull-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expressionADAM13 disintegrin and cysteine-rich domains bind to the second heparin-binding domain of fibronectin.Selective modulation of integrin-mediated cell migration by distinct ADAM family membersCross talk between tetanus neurotoxin-insensitive vesicle-associated membrane protein-mediated transport and L1-mediated adhesion.Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis.Initial activation of EpCAM cleavage via cell-to-cell contact.L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions.An integrin-contactin complex regulates CNS myelination by differential Fyn phosphorylation.ADAM10 is expressed in human podocytes and found in urinary vesicles of patients with glomerular kidney diseasesL1 is a potential marker for poorly-differentiated pancreatic neuroendocrine carcinoma.Inside-out regulation of L1 conformation, integrin binding, proteolysis, and concomitant cell migration.Circulating levels of cell adhesion molecule L1 as a prognostic marker in gastrointestinal stromal tumor patients.PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cellsL1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowthSoluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion.L1 cell adhesion molecule found in human CSF varies as a function of age.Serpins promote cancer cell survival and vascular co-option in brain metastasisAntibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.UCHL1 regulates ubiquitination and recycling of the neural cell adhesion molecule NCAM.L1CAM in human cancer.Low cholesterol triggers membrane microdomain-dependent CD44 shedding and suppresses tumor cell migration.Epigenetic regulation of L1CAM in endometrial carcinoma: comparison to cancer-testis (CT-X) antigensCalmodulin adopts an extended conformation when interacting with L-selectin in membranes.L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach.IgLON cell adhesion molecules are shed from the cell surface of cortical neurons to promote neuronal growth.EphB regulates L1 phosphorylation during retinocollicular mapping.L1 stimulation of human glioma cell motility correlates with FAK activation.
P2860
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P2860
Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@ast
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@en
type
label
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@ast
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@en
prefLabel
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@ast
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@en
P2093
P2860
P356
P1476
Ectodomain shedding of L1 adhe ...... utocrine binding to integrins.
@en
P2093
F Fahrenholz
M Oleszewski
N Agmon-Levin
P Altevogt
S Mechtersheimer
P2860
P304
P356
10.1083/JCB.200101099
P407
P577
2001-11-12T00:00:00Z