Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression
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Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosisTransforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cellsPolyamine depletion delays apoptosis of rat intestinal epithelial cellsOncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cellsNeutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapyCollateral expression of proangiogenic and tumorigenic properties in intestinal epithelial cell variants selected for resistance to anoikis3D tissue-engineered model of Ewing's sarcomaThe dark side of Ras: regulation of apoptosis.Oncogenic ras-induced down-regulation of pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells.Development of keratoacanthomas and squamous cell carcinomas in transgenic rabbits with targeted expression of EJras oncogene in epidermis.Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways.Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells.Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesisNew insights into the kinetic resistance to anticancer agentsLoss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts.Bi-transgenic mice reveal that K-rasVal12 augments a p53-independent apoptosis when small intestinal villus enterocytes reenter the cell cycle.Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells.ras-Induced up-regulation of CTP:phosphocholine cytidylyltransferase α contributes to malignant transformation of intestinal epithelial cells.Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cellsFructooligosacharides reduce Pseudomonas aeruginosa PAO1 pathogenicity through distinct mechanisms.E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase.Incorporation of iododeoxyuridine in multicellular glioma spheroids: implications for DNA-targeted radiotherapy using Auger electron emitters.Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cellsAnoikis of colon carcinoma cells triggered by β-catenin loss can be enhanced by tumor necrosis factor receptor 1 antagonists.Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-dimensional in vitro tumor spheroids as a screening model.Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells.Anti-tumorigenic effect of a K-ras ribozyme against human lung cancer cell line heterotransplants in nude mice.Morphology, proliferation and apoptosis of mouse liver epithelial cells cultured as spheroids.Synthetic peptide sequence from the C-terminus of the insulin-like growth factor-I receptor that induces apoptosis and inhibition of tumor growth.Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes.Inhibitors of the Ras signal transduction pathway as potential antitumour agents.Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion.Human duodenal spheroids for noninvasive intracellular pH measurement and quantification of regulation mechanisms under physiological conditions.A transient increase in the activity of Src-family kinases induced by cell detachment delays anoikis of intestinal epithelial cells.Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm.Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells.ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.Multicellular spheroids as an in vitro model in experimental oncology: applications in translational medicine.ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells.
P2860
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P2860
Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Massive programmed cell death ...... nt c-H-ras oncogene expression
@ast
Massive programmed cell death ...... nt c-H-ras oncogene expression
@en
type
label
Massive programmed cell death ...... nt c-H-ras oncogene expression
@ast
Massive programmed cell death ...... nt c-H-ras oncogene expression
@en
prefLabel
Massive programmed cell death ...... nt c-H-ras oncogene expression
@ast
Massive programmed cell death ...... nt c-H-ras oncogene expression
@en
P2093
P2860
P356
P1476
Massive programmed cell death ...... nt c-H-ras oncogene expression
@en
P2093
P2860
P304
P356
10.1083/JCB.131.6.1587
P407
P433
P577
1995-12-01T00:00:00Z