Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain - Wikidata - awgldk - TriplyDB

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain

http://www.wikidata.org/entity/Q36240868

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Pathophysiology of heparan sulphate: many diseases, few drugs Towards understanding the roles of heparan sulfate proteoglycans in Alzheimer's disease Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response Versatile role of heparanase in inflammation Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model Involvement of Heparanase in Empyema: Implication for Novel Therapeutic Approaches Transgenic over-expression of mammalian heparanase delays prion disease onset and progression.The potential of heparanase as a therapeutic target in cancer Heparanase in inflammation and inflammation-associated cancer.Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses.Protective Properties of Neural Extracellular Matrix.Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type Looking Inside the Matrix: Perineuronal Nets in Plasticity, Maladaptive Plasticity and Neurological Disorders.Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy.The Role of Heparanase in the Pathogenesis of Acute Pancreatitis: A Potential Therapeutic Target.Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis.Heparanase expression upregulates platelet adhesion activity and thrombogenicity.Heparanase: From basic research to therapeutic applications in cancer and inflammation.Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies.Heparan Sulfate Proteoglycans as Relays of Neuroinflammation.Upregulated Expression of Heparanase and Heparanase 2 in the Brains of Alzheimer's Disease.

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P2860

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain

http://www.wikidata.org/entity/Q36240868

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Heparanase overexpression impa ...... e of amyloid-β in murine brain

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Heparanase overexpression impa ...... e of amyloid-β in murine brain

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Heparanase overexpression impa ...... e of amyloid-β in murine brain

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Heparanase overexpression impa ...... e of amyloid-β in murine brain

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Heparanase overexpression impa ...... e of amyloid-β in murine brain

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Heparanase overexpression impa ...... e of amyloid-β in murine brain

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Acta Neuropathologica

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Bo Wang

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Elina Hjertström

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Eyal Zcharia

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Feng Gong

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Israel Vlodavsky

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Jin-Ping Li

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Juan Jia

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Lars Lannfelt

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Lars N G Nilsson

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Paul O'Callaghan

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Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase

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The microglial "activation" continuum: from innate to adaptive responses

Does neuroinflammation fan the flame in neurodegenerative diseases?

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Inflammation and Alzheimer's disease

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F4/80, a monoclonal antibody directed specifically against the mouse macrophage

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