Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms.
about
Network medicine approaches to the genetics of complex diseasesBridging the gap between clinicians and systems biologists: from network biology to translational biomedical researchGenetic and genomic analyses as a basis for new diagnostic nosologiesHow variability in clinical phenotypes should guide research into disease mechanisms in asthmaMining kidney toxicogenomic data by using gene co-expression modulesThe Allergic Airway Inflammation Repository--a user-friendly, curated resource of mRNA expression levels in studies of allergic airways.Molecular interaction networks in the analyses of sequence variation and proteomics data.Drug repurposing: a better approach for infectious disease drug discovery?Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment.Modules, networks and systems medicine for understanding disease and aiding diagnosis.Dysregulation of complement system and CD4+ T cell activation pathways implicated in allergic responseJoint GWAS Analysis: Comparing similar GWAS at different genomic resolutions identifies novel pathway associations with six complex diseases.Genetic variants and their interactions in disease risk prediction - machine learning and network perspectivesGenome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases.Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune DisordersConnecting the dots: applications of network medicine in pharmacology and disease.Clinical implications of omics and systems medicine: focus on predictive and individualized treatment.Biomechanisms of Comorbidity: Reviewing Integrative Analyses of Multi-omics Datasets and Electronic Health Records.An Analytic Solution to the Computation of Power and Sample Size for Genetic Association Studies under a Pleiotropic Mode of Inheritance.DrugComboRanker: drug combination discovery based on target network analysisA generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.Breaking free from the chains of pathway annotation: de novo pathway discovery for the analysis of disease processes.New tools and approaches for improved management of inflammatory bowel diseases.A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.Graph Theoretical Analysis of Genome-Scale Data: Examination of Gene Activation Occurring in the Setting of Community-Acquired Pneumonia.ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks.Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor.Proteomics of Aspergillus fumigatus conidia-containing phagolysosomes identifies processes governing immune evasion.Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin
P2860
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P2860
Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Highly interconnected genes in ...... ease-associated polymorphisms.
@ast
Highly interconnected genes in ...... ease-associated polymorphisms.
@en
type
label
Highly interconnected genes in ...... ease-associated polymorphisms.
@ast
Highly interconnected genes in ...... ease-associated polymorphisms.
@en
prefLabel
Highly interconnected genes in ...... ease-associated polymorphisms.
@ast
Highly interconnected genes in ...... ease-associated polymorphisms.
@en
P2093
P2860
P50
P356
P1433
P1476
Highly interconnected genes in ...... ease-associated polymorphisms.
@en
P2093
Gary Rogers
Michael A Langston
Mikael Benson
Rebecka Jörnsten
Sreenivas Chavali
P2860
P2888
P356
10.1186/GB-2012-13-6-R46
P577
2012-06-15T00:00:00Z