Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.
about
Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic propertiesalpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitorsAntinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain.Exendin-4 induces cell adhesion and differentiation and counteracts the invasive potential of human neuroblastoma cellsProtective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating diseaseTargeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid.Cyclic phosphatidic acid relieves osteoarthritis symptoms.Aiming drug discovery at lysophosphatidic acid targets.Protection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA).Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acidAutotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasisVirtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis.Cyclic phosphatidic acid - a unique bioactive phospholipid.Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cellsLysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cellsAutotaxin: its role in biology of melanoma cells and as a pharmacological target.Release of cyclic phosphatidic acid from gelatin-based hydrogels inhibit colon cancer cell growth and migration.Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation.The Role of PPARγ in the Transcriptional Control by Agonists and Antagonists.2-carba cyclic phosphatidic acid suppresses inflammation via regulation of microglial polarisation in the stab-wounded mouse cerebral cortex.
P2860
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P2860
Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@ast
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@en
type
label
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@ast
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@en
prefLabel
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@ast
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@en
P2093
P2860
P1476
Inhibition of transcellular tu ...... s of cyclic phosphatidic acid.
@en
P2093
Ayako Uchiyama
Gabor Tigyi
Hiromu Murofushi
Kimiko Murakami-Murofushi
Masahiro Inoue
Mutsuko Mukai
Nobuyuki Kawai
Shigenori Enoki
Susumu Kobayashi
Tamotsu Niki
P2860
P304
P356
10.1016/J.BBALIP.2006.10.001
P407
P577
2006-10-14T00:00:00Z