Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
about
Skeletal muscle as a therapeutic target for delaying type 1 diabetic complicationsEndocrine regulation of fetal skeletal muscle growth: impact on future metabolic healthAAV-mediated administration of myostatin pro-peptide mutant in adult Ldlr null mice reduces diet-induced hepatosteatosis and arteriosclerosisProkineticin Is a New Linker between Obesity and Cardiovascular DiseasesHigh-fat diet reduces local myostatin-1 paralog expression and alters skeletal muscle lipid content in rainbow trout, Oncorhynchus mykiss.Joint dysfunction and functional decline in middle age myostatin null mice.Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs.Tissue-specific insulin signaling in the regulation of metabolism and aging.Increasing muscle mass improves vascular function in obese (db/db) mice.Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigsGeneration of biallelic knock-out sheep via gene-editing and somatic cell nuclear transferMammalian Mss51 is a skeletal muscle-specific gene modulating cellular metabolism.Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old miceMyostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle.Modeling Energy Dynamics in Mice with Skeletal Muscle Hypertrophy Fed High Calorie Diets.Increasing muscle mass to improve metabolism.ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity.Myostatin inhibition therapy for insulin-deficient type 1 diabetesProkineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions.Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal.Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibitionMyostatin and carbohydrate disturbances.Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2Lean and obese pig breeds exhibit differences in prenatal gene expression profiles of muscle development.Myostatin propeptide mutation of the hypermuscular Compact mice decreases the formation of myostatin and improves insulin sensitivity.Relationship between myostatin and irisin in type 2 diabetes mellitus: a compensatory mechanism to an unfavourable metabolic state?Increased Muscle Mass Protects Against Hypertension and Renal Injury in Obesity
P2860
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P2860
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@ast
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@en
type
label
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@ast
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@en
prefLabel
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@ast
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@en
P2093
P2860
P356
P1433
P1476
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.
@en
P2093
Alexandra C McPherron
Jennifer Portas
Nichole D Bond
Oksana Gavrilova
Tingqing Guo
William Jou
P2860
P304
P356
10.2337/DB11-0915
P407
P577
2012-05-17T00:00:00Z