Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
about
Syntaxin binding mechanism and disease-causing mutations in Munc18-2IκB kinase phosphorylation of SNAP-23 controls platelet secretionCrucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation.Analysis of familial hemophagocytic lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cellsCongenital platelet disorders and understanding of platelet function.The nuts and bolts of the platelet release reaction.Platelets and cancer: a casual or causal relationship: revisited.Platelet secretion and hemostasis require syntaxin-binding protein STXBP5.Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion.Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.VAMP-7 links granule exocytosis to actin reorganization during platelet activation.Munc18b/STXBP2 is required for platelet secretion.Platelet secretion is kinetically heterogeneous in an agonist-responsive manner.Arf6 controls platelet spreading and clot retraction via integrin αIIbβ3 traffickingSequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cellsLysosome-related organelles: unusual compartments become mainstream.Graded defects in cytotoxicity determine severity of hemophagocytic lymphohistiocytosis in humans and miceSecrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?The biogenesis of lysosomes and lysosome-related organellesPlatelet secretion: From haemostasis to wound healing and beyond.Analysis of the proteins associated with platelet detergent resistant membranes.A unique SNARE machinery for exocytosis of cytotoxic granules and platelets granules.SM protein Munc18-2 facilitates transition of Syntaxin 11-mediated lipid mixing to complete fusion for T-lymphocyte cytotoxicity.Platelet secretion in inflammatory and infectious diseases.Syntaxin-4 is implicated in the secretion of antibodies by human plasma cells.The ins and outs of endocytic trafficking in platelet functions.Identification of roles for the SNARE-associated protein, SNAP29, in mouse platelets.Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion.Platelet granule exocytosis: a comparison with chromaffin cells.Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.Syntaxin11 serves as a t-SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes.Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets.Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding.Dynamic Cycling of t-SNARE Acylation Regulates Platelet Exocytosis.The life cycle of platelet granules.Pharmacogenetic studies with oral anticoagulants. Genome-wide association studies in vitamin K antagonist and direct oral anticoagulants.Alterations in platelet secretion differentially affect thrombosis and hemostasis
P2860
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P2860
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
@ast
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
@en
type
label
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
@ast
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
@en
prefLabel
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
@ast
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
@en
P2093
P2860
P1433
P1476
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion
@en
P2093
Alexandra H Filipovich
Jeffery E Pessin
Rania Al Hawas
Shaojing Ye
Zubair A Karim
P2860
P304
P356
10.1182/BLOOD-2012-05-430603
P407
P577
2012-07-05T00:00:00Z