Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.
about
Multiple functions of BCL-2 family proteins.Mitotic events in cerebellar granule progenitor cells that expand cerebellar surface area are critical for normal cerebellar cortical lamination in mice.Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastomaAspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic PathwayHexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastomaTonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastomaATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors.Selective BCL-XL inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells.Molecular Basis of Pediatric Brain Tumors.
P2860
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P2860
Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@ast
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@en
type
label
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@ast
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@en
prefLabel
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@ast
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@en
P2093
P2860
P356
P1433
P1476
Bax deficiency prolongs cerebe ...... alignancy and differentiation.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2012.248
P407
P577
2012-06-18T00:00:00Z