Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.
about
Classic and contemporary approaches to modeling biochemical reactionsCancer systems biology: a network modeling perspectiveSobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology ModelsIn silico model-based inference: a contemporary approach for hypothesis testing in network biologyCell type-specific activation of AKT and ERK signaling pathways by small negatively-charged magnetic nanoparticlesAssociation rate constants of ras-effector interactions are evolutionarily conservedInvestigating differential dynamics of the MAPK signaling cascade using a multi-parametric global sensitivity analysisSelection on Network Dynamics Drives Differential Rates of Protein Domain EvolutionLeveraging models of cell regulation and GWAS data in integrative network-based association studiesCreating and analyzing pathway and protein interaction compendia for modelling signal transduction networksPathway databases and tools for their exploitation: benefits, current limitations and challengesNetwork Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting.Signalling ballet in space and timeSystematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network.Integration of protein abundance and structure data reveals competition in the ErbB signaling network.Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states.Oncofinder, a new method for the analysis of intracellular signaling pathway activation using transcriptomic data.An empirical Bayesian approach for model-based inference of cellular signaling networksLigand-specific sequential regulation of transcription factors for differentiation of MCF-7 cellsSpatio-temporal modeling of signaling protein recruitment to EGFR.Model-based analysis of HER activation in cells co-expressing EGFR, HER2 and HER3Update of KDBI: Kinetic Data of Bio-molecular Interaction database.System theoretical investigation of human epidermal growth factor receptor-mediated signalling.Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistanceInput-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic dataCoupled stochastic spatial and non-spatial simulations of ErbB1 signaling pathways demonstrate the importance of spatial organization in signal transductionThe logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput dataFrom SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathwaysHER/ErbB receptor interactions and signaling patterns in human mammary epithelial cellsDetection of treatment-induced changes in signaling pathways in gastrointestinal stromal tumors using transcriptomic data.Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing.Global genetic response in a cancer cell: self-organized coherent expression dynamics.Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells.Signal transduction networks in cancer: quantitative parameters influence network topologyPhosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.Robust dynamic balance of AP-1 transcription factors in a neuronal gene regulatory networkEpidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity.Spatio-temporal dependence of the signaling response in immune-receptor trafficking networks regulated by cell density: a theoretical model.Timescale analysis of rule-based biochemical reaction networks.Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis
P2860
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P2860
Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Ligand-dependent responses of ...... imental and modeling analyses.
@ast
Ligand-dependent responses of ...... imental and modeling analyses.
@en
type
label
Ligand-dependent responses of ...... imental and modeling analyses.
@ast
Ligand-dependent responses of ...... imental and modeling analyses.
@en
prefLabel
Ligand-dependent responses of ...... imental and modeling analyses.
@ast
Ligand-dependent responses of ...... imental and modeling analyses.
@en
P2860
P50
P356
P1476
Ligand-dependent responses of ...... imental and modeling analyses.
@en
P2093
Mariko Hatakeyama
Noriko Yumoto
P2860
P356
10.1038/MSB4100188
P577
2007-11-13T00:00:00Z