The alpha5beta1 integrin mediates elimination of amyloid-beta peptide and protects against apoptosis.
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Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathwayThe first draft of the endostatin interaction networkBit1 in anoikis resistance and tumor metastasisLaminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathwaysArg-Tyr-Asp (RYD) and Arg-Cys-Asp (RCD) motifs in dendroaspin promote selective inhibition of beta1 and beta3 integrinsAmyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent mannerThe ?5?1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitroSystemic catabolism of Alzheimer's Abeta40 and Abeta42.Positive evolutionary selection of an HD motif on Alzheimer precursor protein orthologues suggests a functional role.Microglial interaction with beta-amyloid: implications for the pathogenesis of Alzheimer's disease.alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathwayJuvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation.αν and β1 Integrins mediate Aβ-induced neurotoxicity in hippocampal neurons via the FAK signaling pathway.The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related DisordersBlueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinaseβ1-integrin-dependent migration of microglia in response to neuron-released α-synuclein.Integrins as receptor targets for neurological disordersPerlecan domain V inhibits amyloid-β induced brain endothelial cell toxicity and restores angiogenic function.The RGD motif and the C-terminal segment of proprotein convertase 1 are critical for its cellular trafficking but not for its intracellular binding to integrin alpha5beta1.Mast cell chymase induces conjunctival epithelial cell apoptosis by a mechanism involving degradation of fibronectin.R-Ras interacts with filamin a to maintain endothelial barrier function.Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides.Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine.Bilateral carotid artery stenosis causes unexpected early changes in brain extracellular matrix and blood-brain barrier integrity in mice.The EBV-Encoded Oncoprotein, LMP1, Induces an Epithelial-to-Mesenchymal Transition (EMT) via Its CTAR1 Domain through Integrin-Mediated ERK-MAPK Signalling.Antibody-mediated inhibition of integrin α5β1 blocks neurotoxic prion peptide PrP106-126-induced activation of BV2 microgliaAmyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells
P2860
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P2860
The alpha5beta1 integrin mediates elimination of amyloid-beta peptide and protects against apoptosis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@ast
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@en
type
label
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@ast
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@en
prefLabel
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@ast
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@en
P2093
P2860
P356
P1476
The alpha5beta1 integrin media ...... nd protects against apoptosis.
@en
P2093
C Nordstedt
E Ruoslahti
M L Matter
P2860
P304
P356
10.1083/JCB.141.4.1019
P407
P577
1998-05-01T00:00:00Z