about
A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changesHuman homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase CThe Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migrationFRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophagesActivation of Rhoa and ROCK are essential for detachment of migrating leukocytesExocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cellsRho GTPases in hematopoiesis and hemopathiesThe Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-SrcHuman neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutationSpatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migrationThe Wiskott-Aldrich syndromeMetallothionein mediates leukocyte chemotaxis.Uveal Melanoma Metastasis ModelsGeneration of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeletonSmall G proteins in the cardiovascular system: physiological and pathological aspectsSubcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration.The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusionsErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways.The RHO-1 RhoGTPase modulates fertility and multiple behaviors in adult C. elegansAssembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migrationThe human WASP-interacting protein, WIP, activates the cell polarity pathway in yeastXPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoCERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migrationWiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cellsActivation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignmentHaematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migrationCdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cellsInhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42Rho GTPases and their effector proteinsRho GTPases control polarity, protrusion, and adhesion during cell movementRegulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonPodoplanin associates with CD44 to promote directional cell migrationRegulation of cell migration and survival by focal adhesion targeting of Lasp-1A role for p21-activated kinase in endothelial cell migration.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
A role for Cdc42 in macrophage chemotaxis.
@ast
A role for Cdc42 in macrophage chemotaxis.
@en
type
label
A role for Cdc42 in macrophage chemotaxis.
@ast
A role for Cdc42 in macrophage chemotaxis.
@en
prefLabel
A role for Cdc42 in macrophage chemotaxis.
@ast
A role for Cdc42 in macrophage chemotaxis.
@en
P2093
P2860
P356
P1476
A role for Cdc42 in macrophage chemotaxis.
@en
P2093
P2860
P304
P356
10.1083/JCB.141.5.1147
P407
P50
P577
1998-06-01T00:00:00Z