Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42 - Wikidata - awgldk - TriplyDB

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

http://www.wikidata.org/entity/Q24603554

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Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells A WASp-VASP complex regulates actin polymerization at the plasma membrane.Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages The Wiskott-Aldrich syndrome Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae.Bee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck Recessive mutations in DOCK6, encoding the guanidine nucleotide exchange factor DOCK6, lead to abnormal actin cytoskeleton organization and Adams-Oliver syndrome Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. Comparison of kinetic properties of Cdc42 binding to the Cdc42-interactive domains Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate Rho GTPases and their effector proteins The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle.SCAR knockouts in Dictyostelium: WASP assumes SCAR's position and upstream regulators in pseudopods Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration.Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases.Direct binding of a fragment of the Wiskott-Aldrich syndrome protein to the C-terminal end of the anaphylatoxin C5a receptor.Retrovirus-mediated WASP gene transfer corrects defective actin polymerization in B cell lines from Wiskott-Aldrich syndrome patients carrying 'null' mutations.WASP is involved in proliferation and differentiation of human haemopoietic progenitors in vitro.Expression of human Wiskott-Aldrich syndrome protein in patients' cells leads to partial correction of a phenotypic abnormality of cell surface glycoproteins.Learning from the slime mold: Dictyostelium and human disease.Human RAS superfamily proteins and related GTPases.Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge.WASp in immune-system organization and function.Distinct roles of Rac GTPases and the UNC-73/Trio and PIX-1 Rac GTP exchange factors in neuroblast protrusion and migration in C. elegans Autoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.A role for Cdc42 in macrophage chemotaxis.Wiskott-Aldrich syndrome protein is an effector of Kit signaling.Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathways Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain.

P2860

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P2860

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

http://www.wikidata.org/entity/Q24603554

description

1996 nî lūn-bûn

@nan

1996 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի մայիսին հրատարակված գիտական հոդված

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1996年の論文

@ja

1996年論文

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1996年論文

@zh-hant

1996年論文

@zh-hk

1996年論文

@zh-mo

1996年論文

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1996年论文

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name

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@ast

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@en

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@nl

type

label

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@ast

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@en

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@nl

prefLabel

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@ast

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@en

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

@nl

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PNAS.93.11.5615

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

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P2093

C L Carpenter

http://www.w3.org/2001/XMLSchema#string

F S Rosen

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K F Tolias

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R Kolluri

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T Kirchhausen

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P2860

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

Small GTP-binding proteins and the regulation of the actin cytoskeleton

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5615-8

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scholarly article

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10.1073/PNAS.93.11.5615

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93

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P5875

14556189

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P698

8643625

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P921

Wiskott-Aldrich syndrome

P932

39296

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