Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.
about
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytesA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisFailure of spinal cord oligodendrocyte development in mice lacking neuregulinRegulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon RegenerationPromoting myelin repair and return of function in multiple sclerosisThe oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelinationTransmembrane neuregulins interact with LIM kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognitionAberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null miceIntegrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelinationA novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cellsLINGO-1 negatively regulates myelination by oligodendrocytesDomain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tailA dual role of erbB2 in myelination and in expansion of the schwann cell precursor poolOligodendrocytes: biology and pathologyImaging genetics of structural brain connectivity and neural integrity markers.The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines.Myelin and disorders that affect the formation and maintenance of this sheath.Functions of N-acetyl-L-aspartate and N-acetyl-L-aspartylglutamate in the vertebrate brain: role in glial cell-specific signaling.The pathogenesis of multiple system atrophy: past, present, and future.A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.Soluble Neuregulin and Schwann Cell Myelination: a Therapeutic Potential for Improving Remyelination of Adult AxonsTargeting oligodendrocyte protection and remyelination in multiple sclerosis.Multiple personalities of neuregulin gene family members.Betacellulin regulates schwann cell proliferation and myelin formation in the injured mouse peripheral nerve.The erbB2 gene is required for the development of terminally differentiated spinal cord oligodendrocytes.CD44 enhances neuregulin signaling by Schwann cells.mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.Glutamate signals through mGluR2 to control Schwann cell differentiation and proliferationNeuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling.Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system.NF-κB signaling regulates myelination in the CNS.Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseasesSynergistic regulation of Schwann cell proliferation by heregulin and forskolin.Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4.Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation.CNS integrins switch growth factor signalling to promote target-dependent survival.The PTEN inhibitor bisperoxovanadium enhances myelination by amplifying IGF-1 signaling in rat and human oligodendrocyte progenitors.
P2860
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P2860
Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@ast
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@en
type
label
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@ast
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@en
prefLabel
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@ast
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@en
P2093
P2860
P356
P1476
Axonal neuregulin signals cell ...... n cells through HER2 and HER3.
@en
P2093
A Goodearl
A Viehöver
T Vartanian
P2860
P304
P356
10.1083/JCB.137.1.211
P407
P577
1997-04-01T00:00:00Z