Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4.
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Receptor binding and biological activity of mammalian expressed sensory and motor neuron-derived factor (SMDF)Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent associationEssential function for ErbB3 in breast cancer proliferationExpression and transactivating functions of the bZIP transcription factor GADD153 in mammary epithelial cellsIdentification of a heregulin binding site in HER3 extracellular domainThe ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cellsNeuregulin-1 type III determines the ensheathment fate of axonsIntramembranous valine linked to schizophrenia is required for neuregulin 1 regulation of the morphological development of cortical neuronsPresynaptic type III neuregulin1-ErbB signaling targets {alpha}7 nicotinic acetylcholine receptors to axonsDynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cellsExpression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor.Immunological Approaches in the Treatment of Metastasized Breast CancerExtracellular domains drive homo- but not hetero-dimerization of erbB receptorsA recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis.Back signaling by the Nrg-1 intracellular domainRational optimization of a bispecific ligand trap targeting EGF receptor family ligands.An isoform of C/EBPβ, LIP, regulates expression of the chemokine receptor CXCR4 and modulates breast cancer cell migration.HER2-Positive Metastatic Breast Cancer Patients Receiving Pertuzumab in a Community Oncology Practice Setting: Treatment Patterns and OutcomesA discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2.ErbB2 dephosphorylation and anti-proliferative effects of neuregulin-1 in ErbB2-overexpressing cells; re-evaluation of their low-affinity interaction.A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.ErbB4 regulates surfactant synthesis and proliferation in adult rat pulmonary epithelial cells.Treatment of human epidermal growth factor receptor 2-overexpressing breast cancer xenografts with multiagent HER-targeted therapy.
P2860
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P2860
Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Formation of a high affinity h ...... of ErbB2 with ErbB3 or ErbB4.
@en
type
label
Formation of a high affinity h ...... of ErbB2 with ErbB3 or ErbB4.
@en
prefLabel
Formation of a high affinity h ...... of ErbB2 with ErbB3 or ErbB4.
@en
P2093
P2860
P1433
P1476
Formation of a high affinity h ...... of ErbB2 with ErbB3 or ErbB4.
@en
P2093
Fitzpatrick VD
Pisacane PI
Sliwkowski MX
Vandlen RL
P2860
P304
P356
10.1016/S0014-5793(98)00737-6
P407
P577
1998-07-01T00:00:00Z