Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease - Wikidata - awgldk - TriplyDB

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

http://www.wikidata.org/entity/Q36283394

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Expanding the Repertoire of Biomarkers for Alzheimer's Disease: Targeted and Non-targeted Approaches Mendelian randomization studies: a review of the approaches used and the quality of reporting The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.Meta-analysis of the rs2075650 polymorphism and risk of Alzheimer disease.2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception.The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid.Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease.Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.The future of blood-based biomarkers for Alzheimer's disease.Coding variants in TREM2 increase risk for Alzheimer's disease Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation A depressive endophenotype of mild cognitive impairment and Alzheimer's disease Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort.Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory.Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40.HDL-cholesterol and apolipoproteins in relation to dementia.APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF.Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1 ABCA1-Mediated Cholesterol Efflux Capacity to Cerebrospinal Fluid Is Reduced in Patients With Mild Cognitive Impairment and Alzheimer's Disease.ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions Finding risk in all the right places Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status.Multiplex biomarkers in blood.Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease.Peripheral apoE isoform levels in cognitively normal APOE ε3/ε4 individuals are associated with regional gray matter volume and cerebral glucose metabolism.Missense variant in TREML2 protects against Alzheimer's disease.Genetic discoveries in AD using CSF amyloid and tau.

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Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

http://www.wikidata.org/entity/Q36283394

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2012年學術文章

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2012年學術文章

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Human Molecular Genetics

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Cerebrospinal fluid APOE level ...... tudies for Alzheimer's disease

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Anthony Hinrichs

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Eve H Pickering

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John S K Kauwe

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Kelly Bales

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Kevin Mayo

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Petra Nowotny

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Sarah Bertelsen

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P2860

SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

Principal components analysis corrects for stratification in genome-wide association studies

Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Mendelian randomization as an instrumental variable approach to causal inference

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Processing of gene expression data generated by quantitative real-time RT-PCR.

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4558-4571

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10.1093/HMG/DDS296

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20

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21

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Carlos Cruchaga

Alzheimer's Disease Neuroimaging Initiative

David M. Holtzman

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2012-07-20T00:00:00Z

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229437374

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22821396

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