The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclusters
about
Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.Human Serum Albumin (HSA) Suppresses the Effects of Glycerol Monolaurate (GML) on Human T Cell Activation and Function.Introduction to thematic series: protein interactions, structures, and networksThe human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion.Zinc-Induced Polymerization of Killer-Cell Ig-like Receptor into Filaments Promotes Its Inhibitory Function at Cytotoxic Immunological Synapses.The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules.Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics.Protein sorting by lipid phase-like domains supports emergent signaling function in B lymphocyte plasma membranes.Development of nanoscale structure in LAT-based signaling complexes.Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters.Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation.
P2860
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P2860
The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclusters
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name
The linker for activation of T ...... ing complexes to microclusters
@ast
The linker for activation of T ...... ing complexes to microclusters
@en
type
label
The linker for activation of T ...... ing complexes to microclusters
@ast
The linker for activation of T ...... ing complexes to microclusters
@en
prefLabel
The linker for activation of T ...... ing complexes to microclusters
@ast
The linker for activation of T ...... ing complexes to microclusters
@en
P2093
P2860
P356
P1476
The linker for activation of T ...... ing complexes to microclusters
@en
P2093
Lakshmi Balagopalan
Lawrence E Samelson
Nathan P Coussens
Robert L Kortum
Valarie A Barr
P2860
P304
26422-26429
P356
10.1074/JBC.R115.665869
P407
P577
2015-09-09T00:00:00Z