ATG4B (Autophagin-1) phosphorylation modulates autophagy.
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O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activityAutophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia.TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy.Fine-tuning autophagy: from transcriptional to posttranslational regulation.Limited and digestive proteolysis: crosstalk between evolutionary conserved pathways.Autophagy-regulating protease Atg4: structure, function, regulation and inhibition.A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B.Rab7b modulates autophagic flux by interacting with Atg4B.Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) InhibitorsLIR and APEAR, two distinct Atg8-binding features within Atg4.MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases.ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells
P2860
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P2860
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
@ast
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
@en
type
label
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
@ast
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
@en
prefLabel
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
@ast
ATG4B (Autophagin-1) phosphorylation modulates autophagy.
@en
P2093
P2860
P356
P1476
ATG4B (Autophagin-1) phosphorylation modulates autophagy
@en
P2093
Chih-Wen Shu
John C Reed
Rachel P Wilkie-Grantham
Shu-Ichi Matsuzawa
Zhifen Yang
P2860
P304
26549-26561
P356
10.1074/JBC.M115.658088
P407
P577
2015-09-16T00:00:00Z