Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. - Wikidata - awgldk - TriplyDB

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

http://www.wikidata.org/entity/Q36287125

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma The protective role of melanin against UV damage in human skin A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B Preponderance of the oncogenic V599E and V599K mutations in B-raf kinase domain is enhanced in melanoma cutaneous/subcutaneous metastases Arsenite-induced alterations of DNA photodamage repair and apoptosis after solar-simulation UVR in mouse keratinocytes in vitro.Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines.The mechanisms of UV mutagenesis.Potential risk factors for cutaneous squamous cell carcinoma include oral contraceptives: results of a nested case-control study Epidemiology of basal cell carcinoma: scholarly review.The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68 Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells.Genetic events and the role of TGF beta in epithelial tumour progression.Melanoma and sun exposure: where are we now?Human papillomavirus and the development of non-melanoma skin cancer The vitamin D receptor: a tumor suppressor in skin.Oxyradicals and DNA damage.Carcinogenesis in mouse and human cells: parallels and paradoxes.Vitamin D and the skin: Physiology and pathophysiology.Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.Differential regulation of cutaneous oncoprotein HPVE6 by wtp53, mutant p53R248W and ΔNp63α is HPV type dependent.Analysis of Tp53 codon 72 polymorphisms, Tp53 mutations, and HPV infection in cutaneous squamous cell carcinomas.Methyl CpG binding protein 2 (MeCP2) enhances photodimer formation at methyl-CpG sites but suppresses dimer deamination.Chronic low-dose ultraviolet-induced mutagenesis in nucleotide excision repair-deficient cells Protective actions of vitamin D in UVB induced skin cancer.Ageing and photoageing of keratinocytes and melanocytes.Protective role of vitamin D signaling in skin cancer formation.Basal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease.Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation.Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra A role for ultraviolet A in solar mutagenesis.Solar-UV-signature mutation prefers TCG to CCG: extrapolative consideration from UVA1-induced mutation spectra in mouse skin.Stepping up melanocytes to the challenge of UV exposure.Molecular epidemiology in environmental health: the potential of tumor suppressor gene p53 as a biomarker.Rotational position of a 5-methylcytosine-containing cyclobutane pyrimidine dimer in a nucleosome greatly affects its deamination rate.UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement UV signature mutations.p38 MAP kinase plays a functional role in UVB-induced mouse skin carcinogenesis.Revisiting the photochemistry of solar UVA in human skin.

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

http://www.wikidata.org/entity/Q36287125

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

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Proceedings of the National Academy of Sciences of the United States of America

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers

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A E Bale

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A J Halperin

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D J Leffell

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H P Baden

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H W Sharma

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J A Simon

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M Gailani

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P E Shapiro

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S Kunala

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P2860

Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9

p53 mutations in human cancers

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

p53 mutations in colorectal cancer

Identification of p53 gene mutations in bladder cancers and urine samples.

Mutation and cancer: a model for human carcinogenesis.

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences.

p53 function and dysfunction.

Overexpression of p53 protein in basal cell carcinomas of human skin

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4216-4220

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9

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Annemarie Ziegler

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