UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement - Wikidata - awgldk - TriplyDB

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

http://www.wikidata.org/entity/Q34961006

about

UVB-induced apoptosis drives clonal expansion during skin tumor development Reconstructing skin cancers using animal models Transcriptome sequencing reveals genome-wide variation in molecular evolutionary rate among ferns IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia.Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells.Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer.Melanoma and sun exposure: where are we now?Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis.Carcinogenesis in mouse and human cells: parallels and paradoxes.Photoprotective actions of topically applied vitamin E.P53 mutations associated with breast, colorectal, liver, lung, and ovarian cancers Future research directions in the use of biomarkers Molecular epidemiology in environmental health: the potential of tumor suppressor gene p53 as a biomarker.Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis.Loss of epithelial p53 and αv integrin cooperate through Akt to induce squamous cell carcinoma yet prevent remodeling of the tumor microenvironment.Caffeine promotes ultraviolet B-induced apoptosis in human keratinocytes without complete DNA repair.A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect.Ligation of high-melting-temperature 'clamp' sequence extends the scanning range of rare point-mutational analysis by constant denaturant capillary electrophoresis (CDCE) to most of the human genome.From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma.Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.Frequent clones of p53-mutated keratinocytes in normal human skin Sunlight and skin cancer: another link revealed p53 and the pathogenesis of skin cancer.Keratinocyte apoptosis in epidermal development and disease.Mutational spectrum of p53 gene in arsenic-related skin cancers from the blackfoot disease endemic area of Taiwan p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer.Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.Current treatment of cutaneous squamous cancer and molecular strategies for its sensitization to new target-based drugs.Synergism between mTOR pathway and ultraviolet radiation in the pathogenesis of squamous cell carcinoma and its implication for solid-organ transplant recipients.Pharmacologic treatment options for advanced epithelial skin cancer.Pathways to Genome-targeted Therapies in Serous Ovarian Cancer.Protective effects of Polypodium leucotomos extract against UVB-induced damage in a model of reconstructed human epidermis.UVB-Induced p21 degradation promotes apoptosis of human keratinocytes.Identification and characterization of a novel cross-link lesion in d(CpC) upon 365-nm irradiation in the presence of 2-methyl-1,4-naphthoquinone.An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.Gain of 11q/cyclin D1 overexpression is an essential early step in skin cancer development and causes abnormal tissue organization and differentiation.p53 gene mutations and photocarcinogenesis.Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes.Use of the alkaline comet assay to detect DNA repair deficiencies in human fibroblasts exposed to UVC, UVB, UVA and gamma-rays.

P2860

Q24656167-01E7CFAD-17AF-4702-B312-5E276D3CFF13 Q27024320-48B55D64-98B9-4CA3-9613-55DCDEAD35A5 Q28596510-ADB8970E-74BB-42DF-AD88-F945DDE588E4 Q30429006-C5315E5A-00C8-44DC-95E1-B26AA0F2852C Q33591760-A5774E18-E61E-4EDC-BB59-ED08E6FDB1E4 Q33616030-620E405D-043D-4CB2-B09A-07E848BE45B0 Q33643298-4D05890B-DCDD-4AC7-A602-CE66465D3CCF Q33706941-05C4E29A-1A6F-49FE-B12C-AE4EB3FAE66C Q33799731-BB08BE6E-D158-4F55-8032-C65828E7CACF Q33846175-BC2546D8-A58C-4F8B-AB09-1A0AFA918679 Q34119194-67611FFE-1511-453F-9986-129B4A5820D1 Q34636497-CAA5360B-CD61-45FC-B77D-1509861F9F0F Q34636869-A9B0BD1E-CD95-4B19-A09D-DC98090CE13D Q34639833-5BC5EDBE-3CBF-40DA-A048-C5B43C2BD4C1 Q34786185-179FC985-584C-49F5-9715-C011C6A5C7EB Q35002203-825C1643-418C-4B86-A9A2-DE2373F7DD5D Q35067683-3828EB0F-E164-48EC-BE0E-CC95AE880342 Q35099489-C47705A5-B68F-4960-9D3A-4E89E7C0BCD9 Q35223140-74733715-11A6-4583-A8FC-AF70943D568D Q35698913-CC550B0D-6A23-423E-8069-AEF183C7612D Q35752935-864BBF01-64C4-492C-A9DA-6C2E65441F72 Q35940911-1E55DA7D-40CB-43E2-A36E-C276BB842C46 Q36001068-A88FE670-28BD-4BE6-8C6E-13D7BE89944A Q36149069-74CB9B25-32FE-4823-849F-59DF068B652D Q36371190-3B25F15D-D9AD-4486-9B3B-EA888AC34AE4 Q36620304-80748A72-7AA3-4C75-90ED-F29B364A8FC6 Q37049524-43F05B55-F0D6-408F-920A-3AD3C4FF63B3 Q37277272-84B986AB-5B62-46AB-A14A-1EF39E7E5E20 Q38045433-F9B9DB37-B0E9-4557-A197-6D3D981B86B3 Q38187197-1DD62B95-4B85-4876-8986-FEC4244910D1 Q38509273-5C411228-D1A3-4183-8CDC-103AD7C06381 Q38621094-56908474-F416-4F6B-B13B-956A3102A2F3 Q38989760-AA0F689E-7361-4C41-8F61-80C5A005653E Q39646895-43F57043-000D-4D5D-8842-EA91598C7960 Q39922631-686BCBDC-359D-44FD-8CF5-DA06D41969D4 Q40198133-242FA174-8E16-45DB-A4A3-77F52254E9BD Q40302213-4C994B19-85D2-4592-A824-62DED36FC23D Q40370722-D79D43A5-C643-4007-B1F8-DECEF30A8854 Q40991506-E82DEFB6-86D7-471E-980E-4D7017E5F7A6 Q41225025-E56E7D3C-31C9-4077-8336-6D6738BA163F

P2860

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

http://www.wikidata.org/entity/Q34961006

description

1994 nî lūn-bûn

@nan

1994 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի հունվարին հրատարակված գիտական հոդված

@hy

1994年の論文

@ja

1994年論文

@yue

1994年論文

@zh-hant

1994年論文

@zh-hk

1994年論文

@zh-mo

1994年論文

@zh-tw

1994年论文

@wuu

name

UV and skin cancer: specific p ...... relevant exposure measurement

@ast

UV and skin cancer: specific p ...... relevant exposure measurement

@en

UV and skin cancer: specific p ...... relevant exposure measurement

@nl

type

label

UV and skin cancer: specific p ...... relevant exposure measurement

@ast

UV and skin cancer: specific p ...... relevant exposure measurement

@en

UV and skin cancer: specific p ...... relevant exposure measurement

@nl

prefLabel

UV and skin cancer: specific p ...... relevant exposure measurement

@ast

UV and skin cancer: specific p ...... relevant exposure measurement

@en

UV and skin cancer: specific p ...... relevant exposure measurement

@nl

P1433

Q34961006-122F0AD7-5228-4086-A12D-D70E6721B800

P1476

Q34961006-0608A529-626A-470F-A4B4-15AC0BE0DE8E

P2093

Q34961006-3B3AE883-B755-434B-B576-2B4E1AF3051B

Q34961006-678C68C1-45CF-46CB-89BE-8408CEAF1E33

Q34961006-88FA4899-A268-4348-994E-44DE929DE40A

Q34961006-C8FEFE0E-83B6-4AD6-818D-423AA5A21117

Q34961006-CE070E28-AEC0-4C6A-9424-A4049376B69C

P2860

Q34961006-01203206-036E-4464-AB1F-2E985024DDDB

Q34961006-07EE358B-8A91-43A2-9F8C-8D0BAE958FE6

Q34961006-0A2CA08E-9ACE-4DA3-9DA8-10841BA6F641

Q34961006-0FD530FA-519A-4FBB-93BF-EF85AF66997B

Q34961006-1CB3D4E0-B7D9-47B8-9612-496225DAD186

Q34961006-269D4015-29FC-4134-9074-8883F21596C2

Q34961006-27A1D7EA-C995-46A3-BA76-4924DA183FA9

Q34961006-2ABA8811-F344-4297-8620-BE1A3E201154

Q34961006-2D0644F2-DDC4-460D-9DB7-1A5C55A00D2D

Q34961006-2ECC4B96-3B0A-4FB5-8D47-EDCD7733C143

P304

Q34961006-71214A1E-048A-4BF9-AC5E-3582F4545AA5

P31

Q34961006-ACDAE0E8-33F9-45DF-9711-C6FA33A73DD8

P356

Q34961006-C5C871B6-4F1C-478D-9DBD-06EC2BA72436

P407

Q34961006-D7057700-71C7-424E-BA26-8E867C01747B

P433

Q34961006-FF1697A5-CE1D-4345-A2DB-AFA6718199BC

P478

Q34961006-002CECB0-48E3-4954-9B00-6EBAFD8F8800

P50

Q34961006-8366C880-0E00-4EF2-BBA7-30917C6C8762

Q34961006-8BD8BF90-B3D7-4FDF-9B5D-F9F19F82F4D5

P577

Q34961006-9E375EF8-D1D9-49BE-AECC-8E1A906A2AFE

P5875

Q34961006-A3690684-9682-43AF-A544-2AF70F331079

P698

Q34961006-02B149C3-A890-4C0C-8844-612D5E6E603D

P932

Q34961006-FC30E418-FB3F-49FB-8B2E-847B419D5E8E

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

UV and skin cancer: specific p ...... relevant exposure measurement

@en

P2093

H Nakazawa

http://www.w3.org/2001/XMLSchema#string

H Yamasaki

http://www.w3.org/2001/XMLSchema#string

K Nakazawa

http://www.w3.org/2001/XMLSchema#string

N Martel

http://www.w3.org/2001/XMLSchema#string

P L Randell

http://www.w3.org/2001/XMLSchema#string

P2860

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by O(6)-methylguanine.

Angiosarcoma of liver in the manufacture of polyvinyl chloride.

Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.

Molecular epidemiology in cancer risk assessment and prevention: recent progress and avenues for future research.

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Maximizing sensitivity and specificity of PCR by pre-amplification heating

DNA repair and aging in basal cell carcinoma: a molecular epidemiology study.

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice.

Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage.

P304

360-364

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.91.1.360

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

91

http://www.w3.org/2001/XMLSchema#string

P50

Dallas R. English

Bruce Armstrong

P577

1994-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

14921687

http://www.w3.org/2001/XMLSchema#string

P698

8278394

http://www.w3.org/2001/XMLSchema#string

P932

42947

http://www.w3.org/2001/XMLSchema#string