Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells.
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Gene therapy for severe combined immunodeficiency: are we there yet?Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophagesCpG methylation controls reactivation of HIV from latency.Stem cell gene therapy for the beta-chain hemoglobinopathies. Problems and progress.Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients.In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector.Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector.Retroviral expression in embryonic stem cells and hematopoietic stem cells.The beta-globin locus control region versus gene therapy vectors: a struggle for expression.Silencing of gene expression: implications for design of retrovirus vectors.Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs.Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report.In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa.Paucity of HIV DNA methylation in latently infected, resting CD4+ T cells from infected individuals receiving antiretroviral therapyCorrection of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene.Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell functionGene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.Genetic modification of T cells for immunotherapy.NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.Long-term expression of gamma-globin mRNA in mouse erythrocytes from retrovirus vectors containing the human gamma-globin gene fused to the ankyrin-1 promoter.Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation.Slow and Steady Wins The Race? Progress in the Development of Vectors for Gene Therapy of β-Thalassemia and Sickle Cell Disease.Dynamic analysis of proviral induction and De Novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression.Human beta interferon scaffold attachment region inhibits de novo methylation and confers long-term, copy number-dependent expression to a retroviral vector.Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells.In vivo analysis of retroviral enhancer mutations in hematopoietic cells: SP1/EGR1 and ETS/GATA motifs contribute to long terminal repeat specificity.Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa.Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors.Therapeutic levels of human factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A.Long-term silencing of retroviral vectors is resistant to reversal by trichostatin A and 5-azacytidine.One step screening of retroviral producer clones by real time quantitative PCR.Variegation of retroviral vector gene expression in myeloid cells.Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human diseaseIn vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models.Modification of multiple transcriptional regulatory elements in a Moloney murine leukemia virus gene transfer vector circumvents silencing in fibroblast grafts and increases levels of expression of the transferred enzyme.Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium.Bone marrow mesenchymal cells for haemophilia A gene therapy using retroviral vectors with modified long-terminal repeats.Haematopoietic progenitor cells from the common marmoset as targets of gene transduction by retroviral and adenoviral vectors.
P2860
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P2860
Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Consistent, persistent express ...... rine hematopoietic stem cells.
@ast
Consistent, persistent express ...... rine hematopoietic stem cells.
@en
type
label
Consistent, persistent express ...... rine hematopoietic stem cells.
@ast
Consistent, persistent express ...... rine hematopoietic stem cells.
@en
prefLabel
Consistent, persistent express ...... rine hematopoietic stem cells.
@ast
Consistent, persistent express ...... rine hematopoietic stem cells.
@en
P2093
P2860
P356
P1476
Consistent, persistent express ...... rine hematopoietic stem cells.
@en
P2093
P2860
P304
10182-10187
P356
10.1073/PNAS.95.17.10182
P407
P577
1998-08-01T00:00:00Z