Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates. - Wikidata - awgldk - TriplyDB

Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.

Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.

http://www.wikidata.org/entity/Q36288974

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The effect of age on thymic function Early priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and function '"Why me, why now?" Using clinical immunology and epidemiology to explain who gets nontuberculous mycobacterial infection Immune Responses to Influenza Virus and Its Correlation to Age and Inherited Factors Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence.Maintenance of naïve CD8 T cells in nonagenarians by leptin, IGFBP3 and T3.Immune response to the West Nile virus in aged non-human primates.Impact of ageing on the response and repertoire of influenza virus-specific CD4 T cells.Immune memory and aging: an infinite or finite resource?Immune senescence in aged nonhuman primates Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.Age-related dysregulation of CD8+ T cell memory specific for a persistent virus is independent of viral replication The narrowing of the CD8 T cell repertoire in old age Understanding immunosenescence to improve responses to vaccines Nonhuman primate models of human immunology Diversity and clonal selection in the human T-cell repertoire.Accelerated in vivo proliferation of memory phenotype CD4+ T-cells in human HIV-1 infection irrespective of viral chemokine co-receptor tropism.Gp96 SIV Ig immunization induces potent polyepitope specific, multifunctional memory responses in rectal and vaginal mucosa Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes.Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults Immune aging and autoimmunity.Age-related deregulation of naive T cell homeostasis in elderly humans Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques.Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover The interplay between immune maturation, age, chronic viral infection and environment Narrowing of human influenza A virus-specific T cell receptor α and β repertoires with increasing age.Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment.Improving immunity in the elderly: current and future lessons from nonhuman primate models.Age-related changes in CD8 T cell homeostasis and immunity to infection Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates.Use it or lose it: establishment and persistence of T cell memory.Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age.The janus head of T cell aging - autoimmunity and immunodeficiency.Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections Thymopoiesis in elderly human is associated with systemic inflammatory status.Age-associated parallel increase of Foxp3(+)CD4(+) regulatory and CD44(+)CD4(+) memory T cells in SJL/J mice.

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P2860

Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.

http://www.wikidata.org/entity/Q36288974

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2007 nî lūn-bûn

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Proceedings of the National Academy of Sciences of the United States of America

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Dramatic increase in naive T c ...... ive T cells from old primates.

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Alfred Legasse

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Byung Park

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Dragana Nikolich-Zugich

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Ilhem Messaoudi

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Louis J Picker

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Michael K Axthelm

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Miranda Fischer

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Motomi Mori

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Noreen Currier

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Shane Tackitt

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P2860

Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates

The influence of age on T cell generation and TCR diversity

Age-related changes in lymphocyte development and function.

Naïve and memory cell turnover as drivers of CCR5-to-CXCR4 tropism switch in human immunodeficiency virus type 1: implications for therapy.

Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly.

Regulation of naïve and memory T-cell homeostasis.

Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells.

Current concepts of thymic aging.

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance.

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19960-19965

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104

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Janko Nikolich-Žugich

Luka Cicin-Sain

Dragana Nikolich-Zugich

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5791024

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