about
Novel GATA6 mutations in patients with pancreatic agenesis and congenital heart malformationsGenome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyGATA transcription factors as tissue-specific master regulators for induced responsesNatural history of β-cell adaptation and failure in type 2 diabetesTranscription factor regulation of pancreatic organogenesis, differentiation and maturationMany faces of monogenic diabetesThe MafA transcription factor becomes essential to islet β-cells soon after birth.MicroRNA-7a regulates pancreatic β cell function.Pancreas and gallbladder agenesis in a newborn with semilobar holoprosencephaly, a case report.Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development.Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development.Human pluripotent stem cells: an emerging model in developmental biology.Epigenetic regulation of histone modifications and Gata6 gene expression induced by maternal diet in mouse embryoid bodies in a model of developmental programming.TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.Simultaneous gene deletion of gata4 and gata6 leads to early disruption of follicular development and germ cell loss in the murine ovary.Adrenal Development in Mice Requires GATA4 and GATA6 Transcription FactorsPancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesisGATA believe it: new essential regulators of pancreas development.GATA factors in endocrine neoplasiaGATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.Mouse muscle as an ectopic permissive site for human pancreatic development.Development of the human pancreas from foregut to endocrine commitment.SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation.GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk.Transcriptional control of mammalian pancreas organogenesis.Derivation of Endodermal Progenitors From Pluripotent Stem Cells.Insulin-like genes in ascidians: findings in Ciona and hypotheses on the evolutionary origins of the pancreasEpigenetic modifications and long noncoding RNAs influence pancreas development and function.Using stem cells to produce insulin.Unique functions of Gata4 in mouse liver induction and heart developmentGATA6 is essential for endoderm formation from human pluripotent stem cells.The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells.GATA transcription factors: New key regulators in pancreas organogenesis.Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells.A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of miceCase report: maternal mosaicism resulting in inheritance of a novel GATA6 mutation causing pancreatic agenesis and neonatal diabetes mellitus.Studying pancreas development and diabetes using human pluripotent stem cells.A novel GATA6 mutation in a child with congenital heart malformation and neonatal diabetes.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
GATA4 and GATA6 control mouse pancreas organogenesis.
@ast
GATA4 and GATA6 control mouse pancreas organogenesis.
@en
type
label
GATA4 and GATA6 control mouse pancreas organogenesis.
@ast
GATA4 and GATA6 control mouse pancreas organogenesis.
@en
prefLabel
GATA4 and GATA6 control mouse pancreas organogenesis.
@ast
GATA4 and GATA6 control mouse pancreas organogenesis.
@en
P2093
P2860
P356
P1476
GATA4 and GATA6 control mouse pancreas organogenesis
@en
P2093
Bernat Soria
Irene Delgado
Manuel Carrasco
P2860
P304
P356
10.1172/JCI63240
P407
P577
2012-09-24T00:00:00Z