Human survivin is a kinetochore-associated passenger protein. - Wikidata - awgldk - TriplyDB

Human survivin is a kinetochore-associated passenger protein.

Human survivin is a kinetochore-associated passenger protein.

http://www.wikidata.org/entity/Q36293670

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Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.Recruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cells Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs.Ablation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does not Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone Functional analysis of kinetochore assembly in Caenorhabditis elegans.Regulation of cell cycle by the anaphase spindle midzone Survivin 2alpha: a novel Survivin splice variant expressed in human malignancies Survivin and angiotensin-converting enzyme polymorphisms with risk of colorectal cancer: a systematic review and meta-analysis Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis Survivin-derived peptide epitopes and their role for induction of antitumor immunity in hematological malignancies Separating the anti-apoptotic and mitotic roles of survivin Aberrant regulation of survivin by the RB/E2F family of proteins A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity An intravenous (i.v.) route-compatible formulation of FL118, a survivin, Mcl-1, XIAP, and cIAP2 selective inhibitor, improves FL118 antitumor efficacy and therapeutic index (TI)The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney ASAP, a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis Survivin antisense compound inhibits proliferation and promotes apoptosis in liver cancer cells.Localization, dynamics, and function of survivin revealed by expression of functional survivinDsRed fusion proteins in the living cell.Expression of survivin detected by immunohistochemistry in the cytoplasm and in the nucleus is associated with prognosis of leiomyosarcoma and synovial sarcoma patients.A small C-terminal sequence of Aurora B is responsible for localization and function Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma.EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer Survivin expression pattern in the intestine of normoxic and ischemic rats.The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro.Nanoformulated cell-penetrating survivin mutant and its dual actions.The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.Cytokinesis in eukaryotes.Effect of hypoxia on expression of selected proteins involved in regulation of apoptotic activity in striatum of newborn piglets.Prognostic and clinicopathological significance of survivin in colorectal cancer: a meta-analysis

P2860

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P2860

Human survivin is a kinetochore-associated passenger protein.

http://www.wikidata.org/entity/Q36293670

description

2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

@zh-cn

2000年学术文章

@zh-hans

2000年学术文章

@zh-my

2000年学术文章

@zh-sg

2000年學術文章

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2000年學術文章

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2000年學術文章

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name

Human survivin is a kinetochore-associated passenger protein.

@ast

Human survivin is a kinetochore-associated passenger protein.

@en

type

label

Human survivin is a kinetochore-associated passenger protein.

@ast

Human survivin is a kinetochore-associated passenger protein.

@en

prefLabel

Human survivin is a kinetochore-associated passenger protein.

@ast

Human survivin is a kinetochore-associated passenger protein.

@en

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P1433

Journal of Cell Biology

P1476

Human survivin is a kinetochore-associated passenger protein.

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P2093

D A Skoufias

http://www.w3.org/2001/XMLSchema#string

F B Lacroix

http://www.w3.org/2001/XMLSchema#string

R L Margolis

http://www.w3.org/2001/XMLSchema#string

P2860

Control of apoptosis and mitotic spindle checkpoint by survivin

Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement

Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Delay of HeLa cell cleavage into interphase using dihydrocytochalasin B: retention of a postmitotic spindle and telophase disc correlates with synchronous cleavage recovery

Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events.

AIM-1: a mammalian midbody-associated protein required for cytokinesis

A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis

Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

Colocalization of TD-60 and INCENP throughout G2 and mitosis: evidence for their possible interaction in signalling cytokinesis

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1575-1582

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10.1083/JCB.151.7.1575

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7

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151

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Cristiana Mollinari

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2000-12-01T00:00:00Z

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276949890

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11134084

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2150675

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