The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.
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Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationSMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cellsTransforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosisArkadia amplifies TGF-beta superfamily signalling through degradation of Smad7GATA- and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrationsA Tale from TGF-β Superfamily for Thymus Ontogeny and FunctionChromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoNCrk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signalingNegative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)Methylation of Smad6 by protein arginine N-methyltransferase 1Smad expression during kidney developmentSmad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent mannerCandidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor.The Good the Bad and the Ugly of Glycosaminoglycans in Tissue Engineering ApplicationsInduction of Ski Protein Expression upon Luteinization in Rat Granulosa Cells.Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cellsGraded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions.Molecular mechanism of TGF-β signaling pathway in colon carcinogenesis and status of curcumin as chemopreventive strategy.Smad7 regulates terminal maturation of chondrocytes in the growth platePneumolysin-dependent and -independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by Streptococcus pneumoniaeSmad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription.Two major Smad pathways in TGF-beta superfamily signalling.Vascularization of the developing chick limb bud: role of the TGFbeta signalling pathway.Transforming growth factor Beta family: insight into the role of growth factors in regulation of fracture healing biology and potential clinical applications.Smad6 is essential to limit BMP signaling during cartilage developmentThe induction of endochondral bone formation by transforming growth factor-beta(3): experimental studies in the non-human primate Papio ursinus.Relative expression of genes encoding SMAD signal transduction factors in human granulosa cells is correlated with oocyte qualityElevating CLIC4 in Multiple Cell Types Reveals a TGF- Dependent Induction of a Dominant Negative Smad7 Splice Variant.Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopeniaValproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis.Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass.Regulation of TGF-beta family signaling by E3 ubiquitin ligases.Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation.Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling.The roles of TGF-β signaling in carcinogenesis and breast cancer metastasis.SMAD7: a timer of tumor progression targeting TGF-β signaling.Evolutionary roots of arginase expression and regulation.
P2860
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P2860
The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@ast
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@en
type
label
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@ast
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@en
prefLabel
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@ast
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@en
P2093
P2860
P356
P1476
The N domain of Smad7 is essen ...... growth factor-beta signaling.
@en
P2093
P2860
P304
P356
10.1083/JCB.200106023
P407
P577
2001-12-10T00:00:00Z