Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours - Wikidata - awgldk - TriplyDB

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

http://www.wikidata.org/entity/Q36295138

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A gene expression database for the molecular pharmacology of cancer 5-fluorouracil pharmacokinetics: causes for variability and strategies for modulation in cancer chemotherapy.Thymidine kinase in epithelial ovarian cancer: relationship with the other pyrimidine pathway enzymes.Overexpression of the orotate phosphoribosyl-transferase gene enhances the effect of 5-fluorouracil on gastric cancer cell lines.The effect of dihydropyrimidine dehydrogenase deficiency on outcomes with fluorouracil.Mismatch repair proficiency and in vitro response to 5-fluorouracil.Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects.Pharmacogenomics in colorectal carcinomas: future perspectives in personalized therapy.Integrative metabonomics as potential method for diagnosis of thyroid malignancy Biology of colorectal liver metastases: A review.Tissue Metabonomic Phenotyping for Diagnosis and Prognosis of Human Colorectal Cancer.Pharmacogenomics of colorectal cancer prevention and treatment.The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma.Regulation of human dihydropyrimidine dehydrogenase: implications in the pharmacogenetics of 5-FU-based chemotherapy.Pharmacogenomics in colorectal cancer: the first step for individualized-therapy Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression.Synergistic effects of docetaxel and S-1 by modulating the expression of metabolic enzymes of 5-fluorouracil in human gastric cancer cell lines.Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene: identification of a new polymorphism related with effects of 5-fluorouracil.Gene expression in colorectal cancer and in vitro chemosensitivity to 5-fluorouracil: a study of 88 surgical specimens.Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer.Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma.Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer.Tumor dihydropyrimidine dehydrogenase expression is a useful marker in adjuvant therapy with oral fluoropyrimidines after curative resection of colorectal cancer.Dihydropyrimidine dehydrogenase mRNA expression in peripheral blood of rectal cancer patients is significantly associated with residual tumor and distant metastases following resection.Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil.The cancer stem cell marker CD133 is a predictor of the effectiveness of S1+ pegylated interferon α-2b therapy against advanced hepatocellular carcinoma.Regulation of dihydropyrimidine dehydrogenase and pyrimidine nucleoside phosphorylase activities by growth factors and subsequent effects on 5-fluorouracil sensitivity in tumor cells.Relationship between protein levels and gene expression of dihydropyrimidine dehydrogenase in human tumor cells during growth in culture and in nude mice.

P2860

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P2860

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

http://www.wikidata.org/entity/Q36295138

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1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年學術文章

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1998年學術文章

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1998年學術文章

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name

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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type

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Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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British Journal of Cancer

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Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

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P2093

Cassidy J

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Davidson AI

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Keenan RA

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Koruth M

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McLeod HL

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Murray GI

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Sludden J

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P2860

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

Enzymes of uracil catabolism in normal and neoplastic human tissues.

Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil.

Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome.

Distribution and inhibition of dihydrouracil dehydrogenase activities in human tissues using 5-fluorouracil as a substrate.

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile.

Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities.

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10.1038/BJC.1998.73

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9472644

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