Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.
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Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testingAzvudine, a novel nucleoside reverse transcriptase inhibitor showed good drug combination features and better inhibition on drug-resistant strains than lamivudine in vitroCombinations of mutations in the connection domain of human immunodeficiency virus type 1 reverse transcriptase: assessing the impact on nucleoside and nonnucleoside reverse transcriptase inhibitor resistance.Antiretroviral medication adherence and class- specific resistance in a large prospective clinical trial.Anti-human immunodeficiency virus type 1 activity of novel 6-substituted 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives.HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors.The "Connection" Between HIV Drug Resistance and RNase HHepatitis C virus, human immunodeficiency virus and Pseudomonas phage PS5 triad share epitopes of immunogenic determinantsPhenotypic characterization of drug resistance-associated mutations in HIV-1 RT connection and RNase H domains and their correlation with thymidine analogue mutations.Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase.Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients.HIV-1 drug resistance mutations: an updated framework for the second decade of HAARTEffect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility.Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report.Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.Mutations in the C-terminal region of the HIV-1 reverse transcriptase and their correlation with drug resistance associated mutations and antiviral treatment.Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals.A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy.
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P2860
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
Variations in reverse transcri ...... ypic resistance to zidovudine.
@ast
Variations in reverse transcri ...... ypic resistance to zidovudine.
@en
type
label
Variations in reverse transcri ...... ypic resistance to zidovudine.
@ast
Variations in reverse transcri ...... ypic resistance to zidovudine.
@en
prefLabel
Variations in reverse transcri ...... ypic resistance to zidovudine.
@ast
Variations in reverse transcri ...... ypic resistance to zidovudine.
@en
P2093
P2860
P356
P1476
Variations in reverse transcri ...... ypic resistance to zidovudine.
@en
P2093
Bluma G Brenner
Daniela Moisi
Mark A Wainberg
Maureen Oliveira
Michel Ntemgwa
Richard Lalonde
Valeria Micheli
P2860
P304
P356
10.1128/AAC.00646-07
P407
P577
2007-08-27T00:00:00Z