Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
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BK channels: multiple sensors, one activation gateThe voltage-dependent gate in MthK potassium channels is located at the selectivity filterPharmacological gating modulation of small- and intermediate-conductance Ca(2+)-activated K(+) channels (KCa2.x and KCa3.1)Structural correlates of selectivity and inactivation in potassium channels.A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel.New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.Characterization of the PCMBS-dependent modification of KCa3.1 channel gating.Electrostatic influences of charged inner pore residues on the conductance and gating of small conductance Ca2+ activated K+ channels.Negative gating modulation by (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) depends on residues in the inner pore vestibule: pharmacological evidence of deep-pore gating of K(Ca)2 channels.External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.Mechanistic details of BK channel inhibition by the intermediate conductance, Ca2+-activated K channel.Molecular mechanisms of BK channel activation.Structural basis of ion permeation gating in Slo2.1 K+ channels.Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process.Cytoplasmic domains and voltage-dependent potassium channel gating.Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets.Hydrophobic gating in ion channelsOn the simple random-walk models of ion-channel gate dynamics reflecting long-term memory.Molecular mechanisms of Slo2 K+ channel closure.Contribution of the KCa3.1 channel-calmodulin interactions to the regulation of the KCa3.1 gating process.Mechanism of activation at the selectivity filter of the KcsA K+ channel.Structural Determinants for the Selectivity of the Positive KCa3.1 Gating Modulator 5-Methylnaphtho[2,1-d]oxazol-2-amine (SKA-121).The gating mechanism in cyclic nucleotide-gated ion channels.
P2860
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P2860
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@ast
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@en
type
label
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@ast
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@en
prefLabel
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@ast
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@en
P2093
P2860
P356
P1476
Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
@en
P2093
Andrew Bruening-Wright
James Maylie
John P Adelman
Wei-Sheng Lee
P2860
P304
P356
10.1085/JGP.200709828
P577
2007-11-12T00:00:00Z