Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats
about
Sugar activation and glycosylation in PlasmodiumThe protein O-glucosyltransferase Rumi modifies eyes shut to promote rhabdomere separation in DrosophilaFringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligandsNotch-modifying xylosyltransferase structures support an SNi-like retaining mechanismA POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss.Protein O-fucosyltransferase 1 expression impacts myogenic C2C12 cell commitment via the Notch signaling pathwayO-fucose monosaccharide of Drosophila Notch has a temperature-sensitive function and cooperates with O-glucose glycan in Notch transport and Notch signaling activationImpaired O-linked N-acetylglucosaminylation in the endoplasmic reticulum by mutated epidermal growth factor (EGF) domain-specific O-linked N-acetylglucosamine transferase found in Adams-Oliver syndrome.A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptidesJagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.Eukaryotic protein glycosylation: a primer for histochemists and cell biologistsSignificance of glycosylation in Notch signaling.Polysialic acid: biosynthesis, novel functions and applications.Mucin-Type O-Glycosylation in Invertebrates.The multiple roles of epidermal growth factor repeat O-glycans in animal development.Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch.Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking.Novel roles for O-linked glycans in protein folding.Structural and functional studies of differentially O-glycosylated analogs of a thrombin inhibitory peptide - variegin.A phenotype combining hidradenitis suppurativa with Dowling-Degos disease caused by a founder mutation in PSENEN.Tyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance.Characterization of the thrombospondin (TSP)-II gene in Penaeus monodon and a novel role of TSP-like proteins in an induction of shrimp sperm acrosome reaction.Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features.Congenital diseases caused by defective -glycosylation of Notch receptors
P2860
Q26777652-100E911D-ADD1-4A6D-A231-D84161625798Q27311710-47A7768F-488D-49DE-9F96-78899A758D9AQ27683660-34EC5703-09F1-47A3-B963-94208F6735D0Q28505589-07F67DE6-5847-4406-8514-B4814C702DAAQ29347528-16D71B5A-E382-414D-96C7-2E708A031929Q34745434-6CD01262-BF5E-406D-B385-2F60B2D1D0BEQ34801607-2D9A21D0-CA6E-4C53-97B4-6285465CF0CFQ35002856-372D023C-1849-465E-8C80-41AA940C71C1Q35891709-5E6B5F18-16AE-40F7-A4DB-F73C83D559C7Q36479429-66CBA6D1-66A2-4B66-B7DB-F30A0BEA087FQ37187965-B9F18507-01B9-4E68-B049-51B57687182AQ37639440-990B9CC1-6222-487A-9BB7-8A25A5C28E76Q38218592-1E32F3AC-E23E-444A-8FE8-983E59644E2EQ38265379-CE317993-771B-4F52-974A-D02741A5C4BFQ38525129-D87268A4-5677-4F52-8A1E-6A29B09E1591Q38547337-FE43EB93-015A-4651-BE47-BD87CC8BBF90Q38766248-ACBFCF92-702C-417B-B2B2-943EE0CF227AQ41243556-F116915F-6282-4761-99BD-0DD3D9B1FB67Q41685413-A7C0C967-D5BE-42AF-B9E7-46D53FBF1869Q42254297-C33AD507-05BA-4277-A9E5-F512D42E47DAQ47374895-CC48A8F2-E457-4513-9744-253FEF723A4EQ47785002-B5158AFD-99AC-456C-A35D-94262B7C2ADDQ48223715-E9091C7B-B5C3-437B-BC61-E8F95E037605Q48627263-A1664960-437B-4FCA-BD0C-BB1A7079C0EEQ49922672-9867DAE0-95CD-43AC-AAC9-4DFBBE31301BQ58804709-84031902-6472-41B3-BB98-1FA4FE933068
P2860
Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Site-specific O-glucosylation ...... ence of individual EGF repeats
@ast
Site-specific O-glucosylation ...... ence of individual EGF repeats
@en
type
label
Site-specific O-glucosylation ...... ence of individual EGF repeats
@ast
Site-specific O-glucosylation ...... ence of individual EGF repeats
@en
prefLabel
Site-specific O-glucosylation ...... ence of individual EGF repeats
@ast
Site-specific O-glucosylation ...... ence of individual EGF repeats
@en
P2093
P2860
P356
P1476
Site-specific O-glucosylation ...... ence of individual EGF repeats
@en
P2093
Hideyuki Takeuchi
Joshua Kantharia
Maya K Sethi
Robert S Haltiwanger
P2860
P304
33934-33944
P356
10.1074/JBC.M112.401315
P407
P50
P577
2012-08-07T00:00:00Z