The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities
about
Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implicationsParkinson's disease: animal models and dopaminergic cell vulnerabilityConditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegenerationExpression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.Non-motor and motor features in LRRK2 transgenic mice.LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit functionLRRK2: an éminence grise of Wnt-mediated neurogenesis?The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.Insights into LRRK2 function and dysfunction from transgenic and knockout rodent models.LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesisLRRK2 pathobiology in Parkinson's disease.Type II kinase inhibitors show an unexpected inhibition mode against Parkinson's disease-linked LRRK2 mutant G2019S.Mechanisms of Mutant LRRK2 Neurodegeneration.
P2860
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P2860
The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
@wuu
2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@ast
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@en
type
label
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@ast
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@en
prefLabel
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@ast
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@en
P2093
P2860
P356
P1476
The I2020T Leucine-rich repeat ...... aminergic neuron abnormalities
@en
P2093
Etsuro Ohta
Fumiya Obata
Sadahiro Azuma
Sayuri Mori
Takashi Miyajima
Yui Sasaki
P2860
P2888
P356
10.1186/1750-1326-7-15
P577
2012-04-25T00:00:00Z
P5875
P6179
1021272772