Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair
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Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancerDissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry.Targeted inhibition of Polo-like kinase 1 by a novel small-molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells.Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.Pharmacotherapeutic Management of Pancreatic Ductal Adenocarcinoma: Current and Emerging Concepts.WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner.Prolonged mitotic arrest induced by Wee1 inhibition sensitizes breast cancer cells to paclitaxel.PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint.Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma
P2860
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P2860
Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair
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2015 nî lūn-bûn
@nan
2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@ast
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@en
type
label
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@ast
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@en
prefLabel
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@ast
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@en
P2093
P2860
P1433
P1476
Sensitization of Pancreatic Ca ...... omologous Recombination Repair
@en
P2093
David Karnak
Jason S Schreiber
Jonathan Maybaum
Joshua D Parsels
Leslie A Parsels
Mary A Davis
Meredith A Morgan
Tasneem Kausar
Theodore S Lawrence
P2860
P304
P356
10.1016/J.NEO.2015.09.006
P577
2015-10-01T00:00:00Z