CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
about
Phosphorylation: the molecular switch of double-strand break repairPurified human BRCA2 stimulates RAD51-mediated recombinationInteraction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeatsFANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1An ECT2-centralspindlin complex regulates the localization and function of RhoACDK targets Sae2 to control DNA-end resection and homologous recombinationRec2 interplay with both Brh2 and Rad51 balances recombinational repair in Ustilago maydisCyclin-dependent kinase inhibitor therapy for hematologic malignanciesHomologous recombination in DNA repair and DNA damage toleranceInteractions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantumTrypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombinationMaintaining Genome Stability in Defiance of Mitotic DNA DamageThe DNA Damage Response: Making It Safe to Play with KnivesCell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsMolding BRCA2 function through its interacting partnersUnraveling the mechanism of BRCA2 in homologous recombinationRegulation of DNA double-strand break repair pathway choiceMitotic homologous recombination maintains genomic stability and suppresses tumorigenesisCooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombinationMinding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forksHigh RAD51 mRNA expression characterize estrogen receptor-positive/progesteron receptor-negative breast cancer and is associated with patient's outcomeRepair at single targeted DNA double-strand breaks in pluripotent and differentiated human cellsChemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cellsHomologs of breast cancer genes in plantsATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaksBRCA2 BRC motifs bind RAD51-DNA filaments.Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques.Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions.DNA binding, annealing, and strand exchange activities of Brh2 protein from Ustilago maydis.The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A.The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants.The role of the Fanconi anemia network in the response to DNA replication stress.A syngeneic variance library for functional annotation of human variation: application to BRCA2Remodeling of DNA replication structures by the branch point translocase FANCMCellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C.GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
P2860
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P2860
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
CDK-dependent phosphorylation ...... ism for recombinational repair
@ast
CDK-dependent phosphorylation ...... ism for recombinational repair
@en
CDK-dependent phosphorylation ...... ism for recombinational repair
@en-gb
CDK-dependent phosphorylation ...... ism for recombinational repair
@nl
type
label
CDK-dependent phosphorylation ...... ism for recombinational repair
@ast
CDK-dependent phosphorylation ...... ism for recombinational repair
@en
CDK-dependent phosphorylation ...... ism for recombinational repair
@en-gb
CDK-dependent phosphorylation ...... ism for recombinational repair
@nl
prefLabel
CDK-dependent phosphorylation ...... ism for recombinational repair
@ast
CDK-dependent phosphorylation ...... ism for recombinational repair
@en
CDK-dependent phosphorylation ...... ism for recombinational repair
@en-gb
CDK-dependent phosphorylation ...... ism for recombinational repair
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
CDK-dependent phosphorylation ...... ism for recombinational repair
@en
P2093
Julian Gannon
Nicole Christ
P2860
P2888
P304
P3181
P356
10.1038/NATURE03404
P407
P577
2005-03-31T00:00:00Z
P5875
P6179
1043753182