Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. - Wikidata - awgldk - TriplyDB

Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

http://www.wikidata.org/entity/Q36315139

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Characterization of uncultivable bat influenza virus using a replicative synthetic virus Animal models for Ebola and Marburg virus infections Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis Filoviral immune evasion mechanisms Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A)Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1 Filoviruses: One of These Things is (not) Like the Other Mouse models for filovirus infections Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory Domain The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity Crystal Structure of Marburg Virus VP24 The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway Interferons and viruses: an evolutionary arms race of molecular interactions Neglected filoviruses Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery Risks Posed by Reston, the Forgotten Ebolavirus.Disruption of type I interferon signaling by the nonstructural protein of severe fever with thrombocytopenia syndrome virus via the hijacking of STAT2 and STAT1 into inclusion bodies Severe fever with thrombocytopenia syndrome virus inhibits exogenous Type I IFN signaling pathway through its NSs invitro Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen.Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye.Leishmania donovani amastigotes impair gamma interferon-induced STAT1alpha nuclear translocation by blocking the interaction between STAT1alpha and importin-alpha5 Interplay between innate immunity and negative-strand RNA viruses: towards a rational model The Ebola virus VP24 protein prevents hnRNP C1/C2 binding to karyopherin α1 and partially alters its nuclear import.A novel life cycle modeling system for Ebola virus shows a genome length-dependent role of VP24 in virus infectivity Antagonism of type I interferon responses by new world hantaviruses How Ebola virus counters the interferon system.Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design.Camouflage and misdirection: the full-on assault of ebola virus disease Molecular mechanisms of Ebola virus pathogenesis: focus on cell death.Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.An upstream open reading frame modulates ebola virus polymerase translation and virus replication.Marburg virus VP40 antagonizes interferon signaling in a species-specific manner.Evasion of the interferon-mediated antiviral response by filoviruses.Contribution of Sec61α to the life cycle of Ebola virus.The Ebolavirus VP24 protein blocks phosphorylation of p38 mitogen-activated protein kinase.

P2860

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P2860

Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

http://www.wikidata.org/entity/Q36315139

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Ebola virus VP24 proteins inhi ...... proteins with activated STAT1.

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Ebola virus VP24 proteins inhi ...... proteins with activated STAT1.

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type

label

Ebola virus VP24 proteins inhi ...... proteins with activated STAT1.

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Ebola virus VP24 proteins inhi ...... proteins with activated STAT1.

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prefLabel

Ebola virus VP24 proteins inhi ...... proteins with activated STAT1.

@ast

Ebola virus VP24 proteins inhi ...... proteins with activated STAT1.

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Ebola virus VP24 proteins inhi ...... proteins with activated STAT1

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P2093

Charalampos Valmas

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Freddy Mauricio Sanchez

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St Patrick Reid

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P2860

Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family

Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein

Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1

Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor

Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL

Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus

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13469-13477

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scholarly article

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10.1128/JVI.01097-07

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24

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81

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Osvaldo Martinez

Christopher F Basler

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5917551

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17928350

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2168840

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