Hedgehog pathway inhibition and the race against tumor evolution
about
Smoothened variants explain the majority of drug resistance in basal cell carcinomaStructural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancerAdvanced treatment for basal cell carcinomas.Proteomic analysis of PTCH1+/- fibroblast lysate and conditioned culture media isolated from the skin of healthy subjects and nevoid basal cell carcinoma syndrome patients.De novo branching cascades for structural and functional diversity in small molecules.Advances in the management of basal cell carcinoma.Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemiaTargeting the Hedgehog signaling pathway in cancer: beyond Smoothened.Mechanisms and insights into drug resistance in cancerSurvivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cellsNevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome)Hedgehog signaling in prostate cancer and its therapeutic implicationA computation using mutually exclusive processing is sufficient to identify specific Hedgehog signaling components.Nonclassical hedgehog-GLI signaling and its clinical implications.Inhibition of Hedgehog signaling in the gastrointestinal tract: targeting the cancer microenvironment.Hedgehog signaling pathway as a new therapeutic target in pancreatic cancer.Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.Scaffold Diversity Synthesis and Its Application in Probe and Drug Discovery.Clonal cooperativity in heterogenous cancers.Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation."Patch"ing up our tumor signaling knowledge.The Hedgehog inhibitor cyclopamine impairs the benefits of immunotherapy with activated T and NK lymphocytes derived from patients with advanced cancer.GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases.AKT1 Activation is Obligatory for Spontaneous BCC Tumor Growth in a Murine Model that Mimics Some Features of Basal Cell Nevus Syndrome."Atypical" regulation of Hedgehog-dependent cancers.Merkel Cell Carcinoma with a Suppressor of Fused (SUFU) Mutation: Case Report and Potential Therapeutic Implications.Advanced Basal Cell Carcinoma: Epidemiology and Therapeutic Innovations.Strategies to target the Hedgehog signaling pathway for cancer therapy.SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas.Update on Genetic Conditions Affecting the Skin and the Kidneys.Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog SignalingYAP-TEAD signaling promotes basal cell carcinoma development via a c-JUN/AP1 axisWidespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy
P2860
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P2860
Hedgehog pathway inhibition and the race against tumor evolution
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Hedgehog pathway inhibition and the race against tumor evolution
@ast
Hedgehog pathway inhibition and the race against tumor evolution
@en
type
label
Hedgehog pathway inhibition and the race against tumor evolution
@ast
Hedgehog pathway inhibition and the race against tumor evolution
@en
prefLabel
Hedgehog pathway inhibition and the race against tumor evolution
@ast
Hedgehog pathway inhibition and the race against tumor evolution
@en
P2860
P356
P1476
Hedgehog pathway inhibition and the race against tumor evolution
@en
P2093
Anne Lynn S Chang
Anthony E Oro
P2860
P304
P356
10.1083/JCB.201207140
P407
P50
P577
2012-10-01T00:00:00Z