Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics. - Wikidata - awgldk - TriplyDB

Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics.

Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics.

http://www.wikidata.org/entity/Q36322983

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ZW10 links mitotic checkpoint signaling to the structural kinetochore.Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK Histone H1 is essential for mitotic chromosome architecture and segregation in Xenopus laevis egg extracts.Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling Review series: The functions and consequences of force at kinetochores Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.Fast, multi-dimensional and simultaneous kymograph-like particle dynamics (SkyPad) analysis Kinetochore-independent chromosome poleward movement during anaphase of meiosis II in mouse eggs Motile properties of the bi-directional kinesin-5 Cin8 are affected by phosphorylation in its motor domain.Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B.Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy.The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement.Dissection of CENP-C-directed centromere and kinetochore assembly Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro.Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis.Measuring nanometer scale gradients in spindle microtubule dynamics using model convolution microscopy Xorbit/CLASP links dynamic microtubules to chromosomes in the Xenopus meiotic spindle.Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells.Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle.Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle.The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.The coupling between sister kinetochore directional instability and oscillations in centromere stretch in metaphase PtK1 cells.Pac-man motility of kinetochores unleashed by laser microsurgery.Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells.Deformations within moving kinetochores reveal different sites of active and passive force generation.Microtubule plus-end dynamics in Xenopus egg extract spindles.Pericentromere tension is self-regulated by spindle structure in metaphase.Bipolarization and poleward flux correlate during Xenopus extract spindle assembly.Direct visualization of microtubule flux during metaphase and anaphase in crane-fly spermatocytes.Analysis of a spindle pole body mutant reveals a defect in biorientation and illuminates spindle forces Kinetochore fibre dynamics outside the context of the spindle during anaphase.The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly.Model based dynamics analysis in live cell microtubule images.A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.

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P2860

Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics.

http://www.wikidata.org/entity/Q36322983

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2003 nî lūn-bûn

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Direct observation of microtub ...... cations for spindle mechanics.

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Direct observation of microtub ...... cations for spindle mechanics.

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Direct observation of microtub ...... cations for spindle mechanics.

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Direct observation of microtub ...... cations for spindle mechanics.

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P2093

Aaron Straight

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Edward D Salmon

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Paul Maddox

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Peg Coughlin

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Timothy J Mitchison

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P2860

EB1 targets to kinetochores with attached, polymerizing microtubules

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement

Microtubule treadmilling in vitro investigated by fluorescence speckle and confocal microscopy.

The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work.

Microtubule flux and sliding in mitotic spindles of Drosophila embryos.

The polarity and dynamics of microtubule assembly in the budding yeast Saccharomyces cerevisiae.

Spinning disk confocal microscope system for rapid high-resolution, multimode, fluorescence speckle microscopy and green fluorescent protein imaging in living cells.

Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells.

Mitosis: a history of division.

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