RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages.
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Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by meninEarly events in cell spreading as a model for quantitative analysis of biomechanical eventsMechanotransduction and extracellular matrix homeostasisA novel 3D fibril force assay implicates src in tumor cell force generation in collagen networksReinforcement versus fluidization in cytoskeletal mechanoresponsivenessQuantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreadingExpression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channelsRegulation of cell adhesion by protein-tyrosine phosphatases. I. Cell-matrix adhesionProtein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelinationIntegrins direct Src family kinases to regulate distinct phases of oligodendrocyte developmentInteractions of the protein-tyrosine phosphatase-α with the focal adhesion targeting domain of focal adhesion kinase are involved in interleukin-1 signaling in fibroblasts.N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.Loss of function studies in mice and genetic association link receptor protein tyrosine phosphatase α to schizophrenia.Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras.Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flowTalin depletion reveals independence of initial cell spreading from integrin activation and traction.Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransductionTwo distinct phases of calcium signalling under flow.Cells test substrate rigidity by local contractions on submicrometer pillars.Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activationRigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha.Receptor protein tyrosine phosphatases are novel components of a polycystin complexA microfluidic system with optical laser tweezers to study mechanotransduction and focal adhesion recruitment.A minimally invasive method for retrieving single adherent cells of different types from culturesIntracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growthImportance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1-induced matrix metalloproteinase-3 expressionThe switchable integrin adhesome.Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading.Matrix stiffness regulates endothelial cell proliferation through septin 9Fibronectin rigidity response through Fyn and p130Cas recruitment to the leading edgeSrc SH2 arginine 175 is required for cell motility: specific focal adhesion kinase targeting and focal adhesion assembly functionEmergence of airway smooth muscle functions related to structural malleabilityRole of PTPα in the destruction of periodontal connective tissuesMechanical integration of actin and adhesion dynamics in cell migration.Receptor-like protein-tyrosine phosphatase α enhances cell surface expression of neural adhesion molecule NB-3.Fibroblast expression of α-smooth muscle actin, α2β1 integrin and αvβ3 integrin: influence of surface rigidity.Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.Tyrosine phosphatase PTPalpha regulates focal adhesion remodeling through Rac1 activationReceptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation.Multiscale modeling of form and function
P2860
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P2860
RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@ast
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@en
type
label
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@ast
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@en
prefLabel
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@ast
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@en
P2093
P2860
P356
P1476
RPTP-alpha acts as a transduce ...... ntegrin-cytoskeleton linkages.
@en
P2093
Ana Kostic
Gotz von Wichert
Guoying Jiang
Kurt De Vos
Michael P Sheetz
P2860
P304
P356
10.1083/JCB.200211061
P407
P577
2003-04-07T00:00:00Z