Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly
about
Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlothoFGF-10 and specific structural elements of dermatan sulfate size and sulfation promote maximal keratinocyte migration and cellular proliferationNovel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF familyHeparan sulfate proteoglycans: a sugar code for vertebrate development?Heparan sulfate and heparin interactions with proteinsExtracellular distribution of diffusible growth factors controlled by heparan sulfate proteoglycans during mammalian embryogenesisTransport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfateGenetic insights into the mechanisms of Fgf signalingA systems biology approach for the investigation of the heparin/heparan sulfate interactomeMice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethalityAltered heparan sulfate structure in mice with deleted NDST3 gene function.Fell-Muir Lecture: Heparan sulphate and the art of cell regulation: a polymer chain conducts the protein orchestra.Fibroblast growth factors share binding sites in heparan sulphate.Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in miceHeparan sulfate domain organization and sulfation modulate FGF-induced cell signalingZebrafish Ext2 is necessary for Fgf and Wnt signaling, but not for Hh signaling.Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23Syndecans reside in sphingomyelin-enriched low-density fractions of the plasma membrane isolated from a parathyroid cell linePerlecan domain 1 recombinant proteoglycan augments BMP-2 activity and osteogenesis.The Fibroblast Growth Factor signaling pathwayLacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate.The mechanism of lens placode formation: a case of matrix-mediated morphogenesisGenetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development.Ectopic expression screen identifies genes affecting Drosophila mesoderm development including the HSPG Trol.Growth factor-dependent branching of the ureteric bud is modulated by selective 6-O sulfation of heparan sulfateInvestigating the mechanism of the assembly of FGF1-binding heparan sulfate motifsMucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking α-l-iduronidase.2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and functionHedgehogs like it sweet, too.Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.Interactions between heparan sulfate and proteins: the concept of specificity.Biological implications of glycosaminoglycan interactions with haemopoietic cytokines.The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation.Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis.Heparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins.Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development.Heparan sulfate: a key regulator of embryonic stem cell fate.
P2860
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P2860
Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@ast
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@en
type
label
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@ast
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@en
prefLabel
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@ast
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@en
P2860
P356
P1476
Spatial and temporal expressio ...... FGF and FGF receptor assembly
@en
P2093
Alan C Rapraeger
Benjamin L Allen
P2860
P304
P356
10.1083/JCB.200307053
P407
P577
2003-11-01T00:00:00Z