Phosphatidylinositol phosphate 5-kinase Ibeta recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis - Wikidata - awgldk - TriplyDB

Phosphatidylinositol phosphate 5-kinase Ibeta recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis

Phosphatidylinositol phosphate 5-kinase Ibeta recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis

http://www.wikidata.org/entity/Q36325108

about

Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network OCRL1 function in renal epithelial membrane traffic Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexes Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signaling Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking Phosphoinositides: tiny lipids with giant impact on cell regulation Regulation of platelet plug formation by phosphoinositide metabolism Phosphatidylinositol (4,5) bisphosphate controls T cell activation by regulating T cell rigidity and organization PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization PIP kinases define PI4,5P₂signaling specificity by association with effectors Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma The Arf6 GEF GEP100/BRAG2 regulates cell adhesion by controlling endocytosis of beta1 integrins.Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Role of lipids and actin in the formation of clathrin-coated pits.Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources.Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor.A role for Phospholipase D in Drosophila embryonic cellularization.Phosphatidylinositol 4-phosphate 5-kinase alpha is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses.Domain formation in phosphatidylinositol monophosphate/phosphatidylcholine mixed vesicles Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.Phospholipase D2 is required for efficient endocytic recycling of transferrin receptors PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells PIP5KI gamma is required for cardiovascular and neuronal development Bending a membrane: how clathrin affects budding.Lipid regulation of the synaptic vesicle cycle.Dissecting the role of PtdIns(4,5)P2 in endocytosis and recycling of the transferrin receptor Phospholipase D signaling: orchestration by PIP2 and small GTPases.A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.Clathrin regulates the association of PIPKIgamma661 with the AP-2 adaptor beta2 appendage.Oxidative stress decreases phosphatidylinositol 4,5-bisphosphate levels by deactivating phosphatidylinositol- 4-phosphate 5-kinase beta in a Syk-dependent manner.Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting.Polyamine effects on cell function: Possible central role of plasma membrane PI(4,5)P2.Hypothesis review: are clathrin-mediated endocytosis and clathrin-dependent membrane and protein trafficking core pathophysiological processes in schizophrenia and bipolar disorder?On the physiological roles of PIP(2) at cardiac Na+ Ca2+ exchangers and K(ATP) channels: a long journey from membrane biophysics into cell biology.

P2860

Q24534275-34FD001E-643E-4794-81D9-016545263BE0 Q24647354-1F09DB42-00DF-4E3F-8B01-A116060A5F33 Q24671026-C82D801B-DCBA-4CD4-8430-18B60CDCF0BB Q24676005-0A87CB09-32E7-4454-8AA8-6B4C7AC8A5C7 Q26865752-74140956-F414-4628-ADC6-6E0EB8D65753 Q27012953-96B129A7-1BF1-4290-9D29-9A40F0430939 Q27025414-66F05D15-7AB2-4ECC-9560-C9F3A43808FD Q27313688-13061E80-976F-42D7-8BA7-CD59F0D759A2 Q27931907-F30B74A4-43C1-4D5A-98B1-785090A44902 Q28083975-A7C745E0-CA93-4359-B675-898BA179B5BA Q28506799-EE0AFC3C-351B-4C43-8202-48C48F27D079 Q28508195-5B528062-B5AA-4A2A-A52C-2799D22CA961 Q28508645-25B82F75-D68B-4662-8D8D-7C66CB2FA7E5 Q30421860-2F8CA205-0080-48EF-99E7-C90DFE89FA2C Q30479032-9EE81DE5-151F-4708-BAA8-96B90C206F1D Q30481021-7D2DAEE6-46FB-44D1-8263-24EEF67F47F9 Q30492058-CA217656-3AB6-430E-98B2-6D3A843A352C Q30502441-0AB0AC67-4454-442C-9629-F1B9B3A1DFCE Q30509475-A4AC419B-A570-4C62-9F8E-5E2E80D59950 Q30514835-C872C3D6-4E8E-47E6-B1A1-2F606DD72CFA Q33265939-FB993BED-DD77-4C4C-B215-77DDDCEB5032 Q34161263-BAE181C8-A7BE-4C16-90DF-085D5CEE8DBC Q34185632-C0619323-2100-450C-AAC5-70929683CD39 Q34311533-1528B636-A43F-44B2-9C75-E8D7D0A80EFD Q34325673-1DA67656-DA70-42CD-AEFA-9B5CA7CAE1AC Q34558733-5E2F5241-6E26-493E-AD1D-56C48D5106F6 Q34645669-AB01DFE4-418A-4B55-80E1-32E42153F02D Q34695375-71B9CE80-F891-4A1D-B18A-961094097239 Q36026777-F4E951E1-4F2C-4F0A-9D35-20564B590C07 Q36630160-825BE718-747B-4CA4-943C-470279E7E586 Q36716517-DC6918CB-C70C-4BC5-8809-3650331A2195 Q36761494-A168C983-264B-4400-AABF-4D00B7FDF118 Q36893688-A9F40541-AA7A-4329-8FE2-49F882D0150B Q37124863-51AA2887-73D2-404E-A86D-965A0B2B3BC2 Q37185321-AEC715F6-2640-47EA-8DFF-3FCD2D682911 Q37358192-AF9BF60C-9540-4F22-A54D-A9BB09700291 Q37434355-57AE278C-5AAA-4A1B-93A1-309A23960C9C Q37595417-337035F2-4024-4841-AEBD-5D6F4C98BAAD Q37944127-3A88BA6A-9D5F-43EA-9887-656DACAAEB48 Q38573614-DA5B6464-CBD9-4F0F-9A58-79374255678D

P2860

Phosphatidylinositol phosphate 5-kinase Ibeta recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis

http://www.wikidata.org/entity/Q36325108

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年学术文章

@wuu

2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh

2003年學術文章

@zh-hant

name

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@ast

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@en

type

label

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@ast

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@en

prefLabel

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@ast

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@en

P1433

Q36325108-488C1ADF-11E9-4EDA-AA98-D2EB9F8E9A68

P1476

Q36325108-4352EF70-AE5F-4527-AE57-06B8FBAB8B9D

P2093

Q36325108-0818A62A-ED5C-466E-B99A-6E508F153524

Q36325108-6B9E82B9-457F-48C2-9460-A457EFB012A5

Q36325108-7D6CAEF5-7283-46C1-9EFC-1EA05287ABC2

Q36325108-F92042ED-CACF-4A0F-86A5-18EFB76AB2D7

Q36325108-F94C1EE4-72A2-4B16-9D86-C918A686F932

P2860

Q36325108-02444612-37C8-492F-8C02-A21EE086F385

Q36325108-02F9EF84-F723-48E6-87C5-0A6630AA06BB

Q36325108-189C9F30-C59B-44F5-BA49-8EBAA2C8225D

Q36325108-22A5D6A4-FA80-4BFC-8124-9DE001789788

Q36325108-249C385C-3D2E-41B6-AB8A-E69D159A6AED

Q36325108-29428F66-7637-42D9-A468-217BF8E84AAA

Q36325108-35BFFC15-3C9E-441A-82CC-5B69A3AD33A2

Q36325108-4D69AAB8-4793-4A30-BF8F-4E61ECA13B2A

Q36325108-4E32D351-4651-4922-9E21-7FD48EFB9064

Q36325108-50D081EB-C99C-4F62-95D5-7A829F620D0F

P304

Q36325108-75A4B834-AD9F-4129-96F2-DE5B6E48A0C5

P31

Q36325108-8D9BB687-426A-4CEA-AF1E-0AF076ACEF3D

P356

Q36325108-B2D7230E-8025-489C-9269-5C7CDB3476D9

P407

Q36325108-E0CB3D76-89CA-4DD3-BABF-70F6F2592CA4

P433

Q36325108-721CA319-51D7-4958-BC75-2CBB7977BEFD

P478

Q36325108-1518337C-2E32-4F52-845D-63DAD9D7D2BB

P577

Q36325108-ADD67DC9-55EE-4E06-9D49-81C0CD6C4032

P5875

Q36325108-5E17DE32-680E-424B-93B3-2F4BE21F2772

P698

Q36325108-439EE7E6-1334-4CF4-B10B-A7EB8094982F

P932

Q36325108-D1007DA7-6EF7-4770-B972-3146BA29EC53

P356

P1433

Journal of Cell Biology

P1476

Phosphatidylinositol phosphate ...... es of constitutive endocytosis

@en

P2093

David Padrón

http://www.w3.org/2001/XMLSchema#string

Helen Yin

http://www.w3.org/2001/XMLSchema#string

Masaya Yamamoto

http://www.w3.org/2001/XMLSchema#string

Michael G Roth

http://www.w3.org/2001/XMLSchema#string

Ying Jie Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes.

Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

Molecular architecture and functional model of the endocytic AP2 complex

Curvature of clathrin-coated pits driven by epsin

PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse

The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family

P304

693-701

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1083/JCB.200302051

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

162

http://www.w3.org/2001/XMLSchema#string

P577

2003-08-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

10618383

http://www.w3.org/2001/XMLSchema#string

P698

12913109

http://www.w3.org/2001/XMLSchema#string

P932

2173809

http://www.w3.org/2001/XMLSchema#string