The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts - Wikidata - awgldk - TriplyDB

The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts

The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts

http://www.wikidata.org/entity/Q36325944

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Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function T Lymphocyte-Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity Modulation of osteoclast differentiation and bone resorption by Rho GTPases Regulation of osteoclasts by membrane-derived lipid mediators Essential function of dynamin in the invasive properties and actin architecture of v-Src induced podosomes/invadosomes Crystal structure of human osteoclast stimulating factor Spatiotemporal regulation of Src and its substrates at invadosomes Laminin-332-beta1 integrin interactions negatively regulate invadopodia β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5 The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development Kindlin-2 tyrosine phosphorylation and interaction with Src serve as a regulatable switch in the integrin outside-in signaling circuit.c-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton.Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes Paxillin contracts the osteoclast cytoskeleton Regulation of osteoclast structure and function by FAK family kinases Podosomes are present in a postsynaptic apparatus and participate in its maturation.β1A integrin is a master regulator of invadosome organization and function.Analysis of the signaling pathways regulating Src-dependent remodeling of the actin cytoskeleton.Macrophage mesenchymal migration requires podosome stabilization by filamin A Involvement of actin polymerization in podosome dynamics.Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors.A randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients.Hypertrophic stimulation increases beta-actin dynamics in adult feline cardiomyocytes Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts.Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells Osteoclast motility: putting the brakes on bone resorption.Importance of RhoGTPases in formation, characteristics, and functions of invadosomes.Extracellular cholesterol-rich microdomains generated by human macrophages and their potential function in reverse cholesterol transport.TRPV-5 mediates a receptor activator of NF-kappaB (RANK) ligand-induced increase in cytosolic Ca2+ in human osteoclasts and down-regulates bone resorption.GPCR kinase 2 interacting protein 1 (GIT1) regulates osteoclast function and bone mass Src inhibitors in the treatment of metastatic bone disease: rationale and clinical data Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.Podosome organization drives osteoclast-mediated bone resorption.Cofilin activation during podosome belt formation in osteoclasts Adaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase ϵ in osteoclasts.Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148

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The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts

http://www.wikidata.org/entity/Q36325944

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

The tyrosine kinase activity o ...... on of podosomes in osteoclasts

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The tyrosine kinase activity o ...... on of podosomes in osteoclasts

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The tyrosine kinase activity o ...... on of podosomes in osteoclasts

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The tyrosine kinase activity o ...... on of podosomes in osteoclasts

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The tyrosine kinase activity o ...... on of podosomes in osteoclasts

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MBC.E07-03-0227

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Molecular Biology of the Cell

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The tyrosine kinase activity o ...... on of podosomes in osteoclasts

@en

P2093

Archana Sanjay

http://www.w3.org/2001/XMLSchema#string

Cecile Itzstein

http://www.w3.org/2001/XMLSchema#string

Derek Toomre

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Olivier Destaing

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Roland Baron

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William C Horne

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P2860

The architecture of the adhesive apparatus of cultured osteoclasts: from podosome formation to sealing zone assembly

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

Newest findings on the oldest oncogene; how activated src does it

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein.

The formins: active scaffolds that remodel the cytoskeleton

Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility

Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts

Molecular interaction between limb deformity proteins (formins) and Src family kinases

Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110

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394-404

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10.1091/MBC.E07-03-0227

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1

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19

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Pietro De Camilli

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2007-10-31T00:00:00Z

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17978100

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2174183

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