Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix.
about
Microfluidic gradient device for studying mesothelial cell migration and the effect of chronic carbon nanotube exposureChronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cellsPseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].Pseudomonas aeruginosa ExoT Induces Atypical Anoikis Apoptosis in Target Host Cells by Transforming Crk Adaptor Protein into a CytotoxinPseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines.Met receptor tyrosine kinase: enhanced signaling through adapter proteinsDock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migrationProteolysis of the docking protein HEF1 and implications for focal adhesion dynamicsPAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cellsCas and NEDD9 Contribute to Tumor Progression through Dynamic Regulation of the Cytoskeleton.Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesisInhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexesInhibitory receptor signaling via tyrosine phosphorylation of the adaptor CrkRole of CrkII Signaling in RANKL-Induced Osteoclast Differentiation and Function.Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasivenessDynamics and mechanism of p130Cas localization to focal adhesionsRegulation of focal adhesion and cell migration by ANKRD28-DOCK180 interactionThe adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle.CrkII induces serum response factor activation and cellular transformation through its function in Rho activation.Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions.SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.Apoptotic regulation by the Crk adapter protein mediated by interactions with Wee1 and Crm1/exportin.Modulation of HeLa cells spreading by the non-receptor tyrosine kinase ACK-2.The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt.c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase.Regulation of c-SRC activity and function by the adapter protein CASCAS/Crk signalling mediates uptake of Yersinia into human epithelial cells.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.Phosphorylation of p130Cas initiates Rac activation and membrane ruffling.Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cellsMechanisms of CAS substrate domain tyrosine phosphorylation by FAK and SrcSRChing for the substrates of Src.Focal adhesion components are essential for mammalian cell cytokinesis.Cell migration regulates the kinetics of cytokinesis.G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.NHERF-1: modulator of glioblastoma cell migration and invasionChemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization.Targeted therapy against EGFR and VEGFR using ZD6474 enhances the therapeutic potential of UV-B phototherapy in breast cancer cells.Lentivirus-mediated Nox4 shRNA invasion and angiogenesis and enhances radiosensitivity in human glioblastoma.
P2860
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P2860
Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Extracellular-regulated kinase ...... n of the extracellular matrix.
@ast
Extracellular-regulated kinase ...... n of the extracellular matrix.
@en
type
label
Extracellular-regulated kinase ...... n of the extracellular matrix.
@ast
Extracellular-regulated kinase ...... n of the extracellular matrix.
@en
prefLabel
Extracellular-regulated kinase ...... n of the extracellular matrix.
@ast
Extracellular-regulated kinase ...... n of the extracellular matrix.
@en
P2860
P356
P1476
Extracellular-regulated kinase ...... n of the extracellular matrix.
@en
P2093
P2860
P304
P356
10.1083/JCB.149.1.223
P407
P577
2000-04-01T00:00:00Z