Clinical relevance of dominant-negative p73 isoforms for responsiveness to chemotherapy and survival in ovarian cancer: evidence for a crucial p53-p73 cross-talk in vivo.
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Overexpressed TP73 induces apoptosis in medulloblastomaIsoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathwayDeltaNp73alpha regulates MDR1 expression by inhibiting p53 function.BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma.Ubiquitin and ubiquitin-like modifications of the p53 family.p53 Family: Role of Protein Isoforms in Human Cancer.Cross-talk between T-Ag presence and pRb family and p53/p73 signaling in mouse and human medulloblastoma.p73 protein regulates DNA damage repair.Δ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer.Tumour suppressor genes in chemotherapeutic drug response.A Systems Biology Comparison of Ovarian Cancers Implicates Putative Somatic Driver Mutations through Protein-Protein Interaction Models.High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia.PRIMA-1MET induces apoptosis through accumulation of intracellular reactive oxygen species irrespective of p53 status and chemo-sensitivity in epithelial ovarian cancer cellsTherapeutic prospects for p73 and p63: rising from the shadow of p53.Response to microtubule-interacting agents in primary epithelial ovarian cancer cellsModest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysisMapping genetic alterations causing chemoresistance in cancer: identifying the roads by tracking the drivers.The TP73 complex network: ready for clinical translation in cancer?A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.p73 poses a barrier to malignant transformation by limiting anchorage-independent growth.Apoptin induces apoptosis by changing the equilibrium between the stability of TAp73 and ΔNp73 isoforms through ubiquitin ligase PIR2.Induction of the small heat shock protein alphaB-crystallin by genotoxic stress is mediated by p53 and p73.DeltaNp73alpha inhibits PTEN expression in thyroid cancer cells.Alternative splicing of p53 and p73: the novel p53 splice variant p53delta is an independent prognostic marker in ovarian cancer.Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function.Genomic comparison of early-passage conditionally reprogrammed breast cancer cells to their corresponding primary tumors.Clinical implications of the deregulated TP73 isoforms expression in cancer.Truncated isoform Vav3.1 is highly expressed in ovarian cancer stem cells and clinically relevant in predicting prognosis and platinum-response.ΔNp63 expression is associated with poor survival in ovarian cancer
P2860
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P2860
Clinical relevance of dominant-negative p73 isoforms for responsiveness to chemotherapy and survival in ovarian cancer: evidence for a crucial p53-p73 cross-talk in vivo.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@ast
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@en
type
label
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@ast
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@en
prefLabel
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@ast
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@en
P2093
P1476
Clinical relevance of dominant ...... al p53-p73 cross-talk in vivo.
@en
P2093
Adriana Gehmacher
Alain G Zeimet
Astrid Berger
Christian Marth
Daniel Reimer
Elisabeth Mueller-Holzner
Eva Schuster
Gerda Hofstetter
P304
P356
10.1158/1078-0432.CCR-05-0899
P407
P577
2005-12-01T00:00:00Z