The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityMolecular basis of cleft palates in miceSingle strand DNA binding proteins 1 and 2 protect newly replicated telomeresThe Integrator complex controls the termination of transcription at diverse classes of gene targets.Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.Biochemical mechanism of DSB end resection and its regulation.The ATM signaling network in development and disease.Lineage-Specific Genes Are Prominent DNA Damage Hotspots during Leukemic Transformation of B Cell Precursors.Mouse models uncap novel roles of SSBs.Backbone (1)H, (13)C and (15)N resonance assignments of the OB domain of the single stranded DNA-binding protein hSSB2 (NABP1/OBFC2A) and chemical shift mapping of the DNA-binding interface.Mutations in SNRPB, encoding components of the core splicing machinery, cause cerebro-costo-mandibular syndrome.
P2860
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P2860
The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo
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2012 nî lūn-bûn
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2012年の論文
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The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@ast
The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@en
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label
The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@ast
The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@en
prefLabel
The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@ast
The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@en
P2093
P2860
P356
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P1476
The hSSB1 orthologue Obfc2b is ...... he DNA damage response in vivo
@en
P2093
Andre Nussenzweig
Davide F Robbiani
Elisabetta Ferretti
Elsa Callen
Licia Selleri
Stephanie Deroubaix
P2860
P304
P356
10.1038/EMBOJ.2012.247
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P577
2012-08-31T00:00:00Z