Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates
about
Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interfaceToxicology of organophosphorus compounds in view of an increasing terrorist threat.The forgotten or underestimated relevance of biopharmaceutical-based assessments for the oral absorption studies of oxime reactivators.SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015).Recent developments in structural studies on acetylcholinesterase.Cholinesterase reactivators and bioscavengers for pre- and post-exposure treatments of organophosphorus poisoning.Recent developments concerning the application of the Mannich reaction for drug design.New therapeutic approaches and novel alternatives for organophosphate toxicity.
P2860
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P2860
Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@ast
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@en
type
label
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@ast
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@en
prefLabel
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@ast
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@en
P2093
P2860
P50
P356
P1433
P1476
Discovery of New Classes of Co ...... Inhibited by Organophosphates
@en
P2093
Donald W Landry
Francine S Katz
Ilya Trakht
Laura Schneider
Long Ton-That
Michal Luzac
Milan N Stojanovic
Shivani Damera
Timothy H Tran
Viktor Zlatanic
P2860
P304
P356
10.1002/CBIC.201500348
P577
2015-09-09T00:00:00Z