Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
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Alpha 2-macroglobulin synthesis in an astrocyte subpopulationAn alpha 2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-beta 1 in miceNative and activated forms of alpha 2-macroglobulin increase expression of platelet-derived growth factor alpha-receptor in vascular smooth muscle cells. Evidence for autocrine transforming growth factor-beta activity.Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity.Proteinases are isoform-specific regulators of the binding of transforming growth factor beta to alpha 2-macroglobulin.Deposits of alpha 2M in the rheumatoid synovial membrane.Alpha 2-macroglobulin gene expression during rat development studied by in situ hybridization.Biochemical and morphological characterization of the killing of human monocytes by a leukotoxin derived from Actinobacillus actinomycetemcomitansSecretory products of macrophages.Phenotypic expression in human monocyte-derived interleukin-4-induced foreign body giant cells and macrophages in vitro: dependence on material surface properties.Cathepsin D-like activity in neutrophils and monocytesContribution of murine innate serum inhibitors toward interference within influenza virus immune assays.Changes in tissue distribution of rat alpha 1-macroglobulin and pregnancy-associated alpha 1-glycoprotein after inflammatory injury.Extracellular hydrolytic enzymes of rabbit dermal tuberculous lesions and tuberculin reactions collected in skin chambers.Biochemical actions of glucocorticoids on macrophages in culture. Specific inhibition of elastase, collagenase, and plasminogen activator secretion and effects on other metabolic functions.Fibronectin is produced by human macrophages.Constitutive secretion of cystatin C (gamma-trace) by monocytes and macrophages and its downregulation after stimulation.Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor.Secretion of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A.Cystic fibrosis ciliary dyskinesia substances and pulmonary disease. Effects of ciliary dyskinesia substances on neutrophil movement in vitroSynthesis and secretion of alpha-2-macroglobulin by cultured adherent lung cells. Comparison with cell strains derived from other tissues.Modulation of plasminogen activator secretion by activated macrophages: influence of serum factors and correlation with tumoricidal potential.Mechanisms by which activated macrophages inhibit lymphocyte responses.Proteases and their inhibitors in chronic inflammatory periodontal disease.Characterization and role in autoimmune diseases of the polyclonal B-cell activator produced by T-cells-the helper factor.Macrophage activation, chronic inflammation and gastrointestinal disease.Plasminogen activation by t-PA on the surface of human melanoma cells in the presence of alpha 2-macroglobulin secretion.Function of peritoneal exudate cells after abdominal surgery.Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.Immunolocalization of a novel, cytoskeleton-associated polypeptide of Mr 230,000 daltons (p230).Human monocyte spreading induced by factor Bb of the alternative pathway of complement activation. A possible role for C5 in monocyte spreading.Interaction of transforming growth factor-beta-1 with alpha-2-macroglobulin from normal and inflamed equine joints.Evaluation of plasma alpha-2-macroglobulin and interactions with tumour necrosis factor-alpha in horses with endotoxemic signsLipopolysaccharide modulates the expression of alpha 1 proteinase inhibitor and other serine proteinase inhibitors in human monocytes and macrophages.Cell association and degradation of pregnancy zone protein-chymotrypsin complex in cultured human monocytes.Enzyme-linked immunosorbent assay (ELISA) for the measurement of small quantities of alpha 2-macroglobulin.Repression of alpha 2-macroglobulin and stimulation of alpha 1-proteinase inhibitor synthesis in human mononuclear phagocytes by endotoxin.In vivo administration of tolmetin in hyaluronic acid modulates protease levels in postsurgical macrophage-conditioned media.
P2860
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P2860
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年学术文章
@wuu
1977年学术文章
@zh-cn
1977年学术文章
@zh-hans
1977年学术文章
@zh-my
1977年学术文章
@zh-sg
1977年學術文章
@yue
1977年學術文章
@zh
1977年學術文章
@zh-hant
name
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@ast
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@en
type
label
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@ast
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@en
prefLabel
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@ast
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@en
P2093
P2860
P356
P1476
Cultured human monocytes synthesize and secrete alpha2-macroglobulin.
@en
P2093
P2860
P304
P356
10.1084/JEM.145.6.1580
P407
P577
1977-06-01T00:00:00Z