Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
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E-type prostanoid receptor 4 (EP4) in disease and therapyInsights into the prostanoid pathway in the ovary development of the penaeid shrimp Penaeus monodonResveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microgliaProstaglandin E(2) enhances proliferation, dedifferentiation and stem-like properties of rat retinal Müller glial cells in vitroSulforaphane inhibits prostaglandin E2 synthesis by suppressing microsomal prostaglandin E synthase 1.Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice.mPGES-1 deletion impairs aldosterone escape and enhances sodium appetiteNovel human mPGES-1 inhibitors identified through structure-based virtual screening.A maladaptive role for EP4 receptors in mouse mesangial cells.Synergistic suppression of early phase of adipogenesis by microsomal PGE synthase-1 (PTGES1)-produced PGE2 and aldo-keto reductase 1B3-produced PGF2α.Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - role of fat assimilation.Crucial role of perilipin-3 (TIP47) in formation of lipid droplets and PGE2 production in HL-60-derived neutrophilsThe terminal prostaglandin synthases mPGES-1, mPGES-2, and cPGES are all overexpressed in human gliomas.Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients.Microsomal prostaglandin E synthase-1 inhibits PTEN and promotes experimental cholangiocarcinogenesis and tumor progression.COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes.Endothelium-mediated control of vascular tone: COX-1 and COX-2 products.Immunohistochemical Expressions of Main PGE(2) Biosynthesis-related Enzymes and PGE(2) Receptor in Rat NephrogenesisThe Augmenting Effects of Desolvation and Conformational Energy Terms on the Predictions of Docking Programs against mPGES-1.Prostaglandins in cancer cell adhesion, migration, and invasionStructure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme.Mechanistic aspects of COX-2 expression in colorectal neoplasiamPGES-1 deletion impairs diuretic response to acute water loading.Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F2alpha to prostaglandin E2 in bovine endometriumGenetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.Prostaglandin E(2) synthase inhibition as a therapeutic target.Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors.Differential roles of cyclooxygenase-2-related signaling in regulating hypothalamic neuronal activity under various acute stresses.Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue.Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesisIncrease in PGE2 biosynthesis induces a Bax dependent apoptosis correlated to patients' survival in glioblastoma multiforme.Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.Immunohistochemical demonstration of membrane-bound prostaglandin E2 synthase-1 in papillary thyroid carcinoma.Grand challenges in pharmacotherapy of inflammation for the first decades of the 21st century.Regulation of human microsomal prostaglandin E synthase-1 by IL-1β requires a distal enhancer element with a unique role for C/EBPβ.mPGES-1 deletion potentiates urine concentrating capability after water deprivation.Melatonin modulates microsomal PGE synthase 1 and NF-E2-related factor-2-regulated antioxidant enzyme expression in LPS-induced murine peritoneal macrophages.Enzymes involved in the conversion of arachidonic acid to eicosanoids in the skin of atopic dogs.Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.Nuclear factor kappa B and cyclo-oxygenase-2: two concordant players in psoriasis pathogenesis.
P2860
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P2860
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@ast
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@en
type
label
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@ast
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@en
prefLabel
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@ast
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@en
P1433
P1476
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis.
@en
P2093
Ichiro Kudo
Makoto Murakami
P304
P356
10.5483/BMBREP.2005.38.6.633
P577
2005-11-01T00:00:00Z