Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.
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The effect of environmental chemicals on the tumor microenvironmentXenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agentsThe Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.Mitochondrial control by DRP1 in brain tumor initiating cells.Antagonistic effects of selenium on lead-induced autophagy by influencing mitochondrial dynamics in the spleen of chickensMetabolomic and lipidomic analysis of serum from mice exposed to an internal emitter, cesium-137, using a shotgun LC-MS(E) approachMetabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma.Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor.Targeting multiple tyrosine kinase receptors with Dovitinib blocks invasion and the interaction between tumor cells and cancer-associated fibroblasts in breast cancer.A quantitative proteomics analysis of MCF7 breast cancer stem and progenitor cell populations.Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsMitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.Overexpression of monocarboxylate anion transporter 1 and 4 in T24-induced cancer-associated fibroblasts regulates the progression of bladder cancer cells in a 3D microfluidic device.Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironmentLi Fraumeni syndrome, cancer and senescence: a new hypothesis.The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.Triggering the landslide: The tumor-promotional effects of myofibroblastsAltered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming.Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumour cell survival during energy stress.AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms.Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells.Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction.The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming.Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy.Dysfunctional mitochondrial fission impairs cell reprogrammingDisrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis during Cancer Cachexia: A Role for Inflammation.Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in miceResistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming.Epstein-Barr virus latent membrane protein-2A alters mitochondrial dynamics promoting cellular migration mediated by Notch signaling pathway.AKT in stromal fibroblasts controls invasion of epithelial cells.Cancer metabolism: new validated targets for drug discovery.Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis.Implications of mitochondrial network organization in mitochondrial stress signalling in NARP cybrid and Rho0 cells.Temporal depolarization of mitochondria during M phase.Mitochondrial dynamics controls anti-tumour innate immunity by regulating CHIP-IRF1 axis stability.Reactive Oxygen Species and Mitochondrial Dynamics: The Yin and Yang of Mitochondrial Dysfunction and Cancer Progression.Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
P2860
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P2860
Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Mitochondrial fission induces ...... ction, and early tumor growth.
@ast
Mitochondrial fission induces ...... ction, and early tumor growth.
@en
type
label
Mitochondrial fission induces ...... ction, and early tumor growth.
@ast
Mitochondrial fission induces ...... ction, and early tumor growth.
@en
prefLabel
Mitochondrial fission induces ...... ction, and early tumor growth.
@ast
Mitochondrial fission induces ...... ction, and early tumor growth.
@en
P2093
P2860
P50
P356
P1433
P1476
Mitochondrial fission induces ...... ction, and early tumor growth.
@en
P2093
Anthony Howell
Carmela Guido
Mathew C Casimiro
Richard G Pestell
Saveria Aquila
Sebastiano Ando'
Ubaldo E Martinez-Outschoorn
P2860
P304
P356
10.18632/ONCOTARGET.574
P407
P577
2012-08-01T00:00:00Z