about
Structural abnormalities of the cornea and lid resulting from collagen V mutationsHIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesisKetones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolismOxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cellsUnderstanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environmentLoss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formationMurine model of the Ehlers-Danlos syndrome. col5a1 haploinsufficiency disrupts collagen fibril assembly at multiple stagesCytokeratin15-positive basal epithelial cells targeted in graft-versus-host disease express a constitutive antiapoptotic phenotype.Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.Ketone body utilization drives tumor growth and metastasis.Left ventricular dysfunction in murine models of heart failure and in failing human heart is associated with a selective decrease in the expression of caveolin-3.Langerhans cell microgranulomas (pseudo-pautrier abscesses): morphologic diversity, diagnostic implications and pathogenetic mechanisms.The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosisMatrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis.Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connectionNovel expression of vascular cell adhesion molecule-1 (CD106) by squamous epithelium in experimental acute graft-versus-host diseaseIs cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism12E2: a cloned murine dermal cell with features of dermal dendrocytes and capacity to produce pathologic changes resembling early Kaposi's sarcoma.Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration.Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone productionCaveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drugTwo-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cellsMetabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cellsMetabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth.CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis.Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma.Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance.Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsBRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.
P50
Q24301802-C64BDAD8-7234-4D3B-ACC1-256221FD6D98Q24611063-2F364E65-0C7D-4A4B-B194-20BF14B7EB7BQ24611305-683B3FD9-2763-44A3-826D-5E8184906242Q24619475-156C12BA-7C40-436D-AC41-50E787191047Q24620228-BF0D05A6-C469-4416-BA30-0D36D79C1EA5Q28508528-99EBA5C3-9167-4FB4-A3AB-9C775DBDB864Q28508805-7155D906-E6E4-4754-9BFA-C22CF9DEF9B9Q33260305-5813AF09-28D1-45B1-B337-CA7D6A2E5F4FQ34124481-A771975A-B29C-48C7-9CB2-D870D573F2CDQ34168489-90D8C1E4-058A-4A3F-8D81-94F1853B8C3CQ34307146-F078A951-D172-4B65-8794-AAF66F418F07Q34776732-ADD5CAB6-5DFD-4654-A2EF-2A65F352233CQ34928973-03E2DFA8-8726-405D-8C09-C5544C419917Q35013613-11643EAF-266B-465B-9D79-412DD2F00EF6Q35124597-14D3AC9A-5291-4B02-99C4-5553457E16A0Q35124602-FCB80F2E-9C89-47CB-B1DF-20BC92DBBDDFQ35158836-450C492C-CED6-4D80-B478-AA50E618C1B3Q35159014-0B5DF6EB-4C7A-4A7D-B135-B71DDAAAE43DQ35232552-0DFA6CE0-191B-44BD-83C0-633C339FD89AQ35737581-2340A64E-3D1D-406D-A4B9-5D3E6A5F0B89Q35737584-063C969D-D613-4D5A-AEEF-2755838EB61AQ35789037-2CDD5348-15DF-46A9-BD8C-07BB518B25B1Q35801392-4027F975-539C-40EA-B4C8-D18ED20BF8E2Q35843450-5F07375E-7523-4FDA-A3AA-DC006EEC9489Q35911155-B4C58FB3-3923-4CB2-A993-A502D4769B2EQ35928528-D60B8B61-85B0-49EF-B88B-203551A897C6Q35954906-2DD32BBD-6AEF-4316-AE50-6F96F58B9084Q36059690-5DB48AC7-5106-41B4-99CD-96A9294C9C8EQ36071788-6184C12C-EE9E-46FD-B43C-B5C7D5BBB462Q36116239-8ECD128A-0250-4408-B096-E529760DF959Q36304128-E72DD952-75BE-42B3-B95A-98B67A286918Q36304167-9DA2ED17-9FD4-42B9-A068-BA5F596ADE0BQ36338756-EB849728-F775-4A18-9DCB-B4107B71D0BDQ36339227-A567238F-00C9-4465-B886-0B6BFA1522E1Q36426491-57B3A6DE-7F27-4F4E-9D11-FBA42AFDF375Q36426497-57DF2D9B-6E3F-41CE-9435-B84A92445590Q36472233-C717FDE0-2CDA-44EC-BA80-0101433EECC7Q36472242-6D544472-5E62-4B03-AB81-C74C783D200BQ36556326-9317523E-9919-4004-9500-26674BE3C64AQ36556331-6840FCD9-9FAC-41E6-9F1E-913298EBAC4D
P50
name
Diana Whitaker-Menezes
@en
Diana Whitaker-Menezes
@nl
type
label
Diana Whitaker-Menezes
@en
Diana Whitaker-Menezes
@nl
prefLabel
Diana Whitaker-Menezes
@en
Diana Whitaker-Menezes
@nl