Novel method for probing the specificity binding profile of ligands: applications to HIV protease.
about
Rational approaches to improving selectivity in drug designIn silico prediction of mutant HIV-1 proteases cleaving a target sequenceStructural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV proteaseHerpes B virus gD interaction with its human receptor--an in silico analysis approach.Thermodynamic analysis of water molecules at the surface of proteins and applications to binding site prediction and characterization.Molecular Basis for Drug Resistance in HIV-1 ProteaseCharge Optimization Theory for Induced-Fit Ligands.Molecular mechanisms and design principles for promiscuous inhibitors to avoid drug resistance: lessons learned from HIV-1 protease inhibition.Prediction of HIV-1 protease/inhibitor affinity using RosettaLigand.A comparative study of HIV-1 and HTLV-I protease structure and dynamics reveals a conserved residue interaction network.Analysis of HIV protease binding pockets based on 3D shape and electrostatic potential descriptors.Multiple drugs and multiple targets: an analysis of the electrostatic determinants of binding between non-nucleoside HIV-1 reverse transcriptase inhibitors and variants of HIV-1 RT.
P2860
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P2860
Novel method for probing the specificity binding profile of ligands: applications to HIV protease.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
Novel method for probing the s ...... applications to HIV protease.
@ast
Novel method for probing the s ...... applications to HIV protease.
@en
type
label
Novel method for probing the s ...... applications to HIV protease.
@ast
Novel method for probing the s ...... applications to HIV protease.
@en
prefLabel
Novel method for probing the s ...... applications to HIV protease.
@ast
Novel method for probing the s ...... applications to HIV protease.
@en
P2860
P1476
Novel method for probing the s ...... applications to HIV protease.
@en
P2093
Bruce Tidor
Woody Sherman
P2860
P304
P356
10.1111/J.1747-0285.2008.00659.X
P577
2008-03-31T00:00:00Z